SCHEMBL9906193

SCHEMBL9906193

O=C(CSCCC(=O)ON1C(=O)CCC1=O)NCC(=O)Nc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CA9 Q16790 17/20 0.49
▸ CA1 P00915 16/20 0.49
▸ CA2 P00918 16/20 0.49
▸ CA12 O43570 8/20 0.49
▸ CA14 Q9ULX7 4/20 0.48
▸ CA7 P43166 2/20 0.47
▸ USP2 O75604 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1688096 0.95 CA9 (0.52) CA9CA1CA2CA12CA14
SCHEMBL29837449 0.95 CA9 (0.52) CA9CA1CA2CA12CA14
SCHEMBL14426887 0.91 CA9 (0.39) CA9CA1CA2CA12CA14
SCHEMBL9906260 0.90 DNASE1L3 (0.51) CA9CA1CA2CA12CA14
SCHEMBL13678642 0.90 CA9 (0.49) CA9CA1CA2CA12CA14
SCHEMBL14426896 0.88 CA9 (0.56) CA9CA1CA2CA12CA14
SCHEMBL1688099 0.87 FOLH1 (0.51) CA9CA1CA2CA12USP2
SCHEMBL9906325 0.85 FOLH1 (0.54) CA9CA1CA2CA12USP2
SCHEMBL13678665 0.85 ESR1 (0.52) CA9CA1CA2CA12CA14
SCHEMBL9906321 0.85 FOLH1 (0.55) CA9CA1CA2CA12USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673399-B1 DETECTING AND PROFILING MOLECULAR COMPLEXES MONOGRAM BIOSCIENCES INC (US) 2017-04-05 — — EP disclosed
US-8198031-B2 Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening MONOGRAM BIOSCIENCES, INC. (US) 2012-06-12 — — US disclosed
EP-1540347-B1 DETECTING RECEPTOR OLIGOMERIZATION ACLARA BIOSCIENCES INC (US) 2009-09-09 — — EP disclosed
US-20090173631-A1 Single Cell Analysis of Membrane Molecules ACLARA BIOSCIENCES, INC. 2009-07-09 — — US disclosed
US-20090011432-A1 Detecting and Profiling Molecular Complexes MONOGRAM BIOSCIENCES, INC. (US) 2009-01-08 — — US disclosed
US-20080233602-A1 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. 2008-09-25 — — US disclosed
US-7255999-B2 Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide MONOGRAM BIOSCIENCES, INC. (US) 2007-08-14 — — US disclosed
US-7160735-B2 Tagged microparticle compositions and methods MONOGRAM BIOSCIENCES, INC. (US) 2007-01-09 — — US disclosed
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