SCHEMBL9906260

SCHEMBL9906260

O=C(CSCCC(=O)ON1C(=O)CCC1=O)Nc1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ DNASE1L3 Q13609 1/20 0.51
▸ PRMT1 Q99873 1/20 0.51
▸ CA9 Q16790 16/20 0.46
▸ CA1 P00915 15/20 0.46
▸ CA2 P00918 15/20 0.46
▸ CA12 O43570 8/20 0.46
▸ USP2 O75604 2/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ CA14 Q9ULX7 4/20 0.44
▸ CA7 P43166 1/20 0.43
▸ PTGER3 P43115 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ ALPL P05186 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ ALPI P09923 1/20 0.43
▸ ALPG P10696 1/20 0.43
▸ KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29837449 0.95 CA9 (0.52) CA9CA1CA2CA12USP2
SCHEMBL1688096 0.95 CA9 (0.52) CA9CA1CA2CA12USP2
SCHEMBL9906193 0.90 CA9 (0.49) CA9CA1CA2CA12USP2
SCHEMBL13678642 0.90 CA9 (0.49) CA9CA1CA2CA12USP2
SCHEMBL9906226 0.87 ALB (0.49) DNASE1L3PRMT1CA9USP2L3MBTL1
SCHEMBL14426887 0.87 CA9 (0.39) DNASE1L3PRMT1CA9CA1CA2
SCHEMBL9906261 0.85 ALB (0.52) —
SCHEMBL9906228 0.85 ALB (0.45) DNASE1L3PRMT1CA9USP2L3MBTL1
SCHEMBL9906229 0.84 FOLH1 (0.51) DNASE1L3PRMT1USP2L3MBTL1
SCHEMBL14526777 0.84 CA9 (0.56) DNASE1L3PRMT1CA9CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673399-B1 DETECTING AND PROFILING MOLECULAR COMPLEXES MONOGRAM BIOSCIENCES INC (US) 2017-04-05 — — EP disclosed
US-9110075-B2 Compositions for analyzing proteins MONOGRAM BIOSCIENCES, INC. (US) 2015-08-18 — — US disclosed
US-8198031-B2 Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening MONOGRAM BIOSCIENCES, INC. (US) 2012-06-12 — — US disclosed
EP-1540347-B1 DETECTING RECEPTOR OLIGOMERIZATION ACLARA BIOSCIENCES INC (US) 2009-09-09 — — EP disclosed
US-20090011432-A1 Detecting and Profiling Molecular Complexes MONOGRAM BIOSCIENCES, INC. (US) 2009-01-08 — — US disclosed
US-20080233602-A1 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. 2008-09-25 — — US disclosed
US-7255999-B2 Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide MONOGRAM BIOSCIENCES, INC. (US) 2007-08-14 — — US disclosed
US-7160735-B2 Tagged microparticle compositions and methods MONOGRAM BIOSCIENCES, INC. (US) 2007-01-09 — — US disclosed
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