Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 2/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | HTRA2 | O43464 | 8/20 | 0.43 |
| ▸ | HTRA1 | Q92743 | 8/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13780484 | 0.98 | FOLH1 (0.47) | FOLH1ALBSLC5A2AVPR2OXTR | |
| SCHEMBL13678657 | 0.94 | FOLH1 (0.46) | FOLH1ALBSLC5A2AVPR2OXTR | |
| SCHEMBL13678652 | 0.91 | CA9 (0.43) | FOLH1ALBSLC5A2CA9 | |
| SCHEMBL13678641 | 0.87 | ALB (0.48) | FOLH1ALBSLC5A2AVPR2OXTR | |
| SCHEMBL18699631 | 0.85 | ALB (0.56) | FOLH1ALBSLC5A2AVPR2OXTR | |
| SCHEMBL9906264 | 0.85 | ALB (0.48) | FOLH1ALBSLC5A2AVPR2OXTR | |
| SCHEMBL14140516 | 0.84 | HTRA2 (0.38) | FOLH1ALBSLC5A2HTRA2HTRA1 | |
| SCHEMBL1688103 | 0.83 | FOLH1 (0.55) | FOLH1ALBSLC5A2AVPR2OXTR | |
| SCHEMBL9906263 | 0.82 | FOLH1 (0.46) | FOLH1ALBSLC5A2AVPR2OXTR | |
| SCHEMBL14426891 | 0.81 | HTRA2 (0.43) | FOLH1ALBSLC5A2AVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198031-B2 | Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening | MONOGRAM BIOSCIENCES, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20080233602-A1 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. | 2008-09-25 | — | — | US | disclosed |