SCHEMBL9906228

SCHEMBL9906228

CC(C)(CNC(=O)CSCCC(=O)ON1C(=O)CCC1=O)CNC(=O)c1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 2/20 0.45
▸ HTRA2 O43464 7/20 0.43
▸ HTRA1 Q92743 7/20 0.43
▸ ESR1 P03372 1/20 0.42
▸ FOLH1 Q04609 2/20 0.42
▸ DNASE1L3 Q13609 1/20 0.42
▸ PRMT1 Q99873 1/20 0.42
▸ USP2 O75604 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9906226 0.92 ALB (0.49) ALBHTRA2HTRA1ESR1FOLH1
SCHEMBL13678645 0.92 ALB (0.45) ALBHTRA2HTRA1ESR1FOLH1
SCHEMBL9906261 0.91 ALB (0.52) ALBHTRA2HTRA1FOLH1
SCHEMBL9906229 0.89 FOLH1 (0.51) ALBHTRA2HTRA1ESR1FOLH1
SCHEMBL9906192 0.88 ALB (0.49) ALBHTRA2HTRA1ESR1FOLH1
SCHEMBL1688099 0.88 FOLH1 (0.51) ALBESR1FOLH1USP2L3MBTL1
SCHEMBL9906325 0.87 FOLH1 (0.54) ALBHTRA2HTRA1ESR1FOLH1
SCHEMBL9906321 0.86 FOLH1 (0.55) ALBHTRA2HTRA1ESR1FOLH1
SCHEMBL13678665 0.86 ESR1 (0.52) ALBESR1FOLH1USP2L3MBTL1
SCHEMBL14526054 0.85 FOLH1 (0.41) ALBHTRA2HTRA1ESR1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673399-B1 DETECTING AND PROFILING MOLECULAR COMPLEXES MONOGRAM BIOSCIENCES INC (US) 2017-04-05 — — EP disclosed
US-8198031-B2 Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening MONOGRAM BIOSCIENCES, INC. (US) 2012-06-12 — — US disclosed
US-20090173631-A1 Single Cell Analysis of Membrane Molecules ACLARA BIOSCIENCES, INC. 2009-07-09 — — US disclosed
US-20090011432-A1 Detecting and Profiling Molecular Complexes MONOGRAM BIOSCIENCES, INC. (US) 2009-01-08 — — US disclosed
US-20080233602-A1 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. 2008-09-25 — — US disclosed
US-7402397-B2 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. (US) 2008-07-22 — — US disclosed
US-7255999-B2 Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide MONOGRAM BIOSCIENCES, INC. (US) 2007-08-14 — — US disclosed
US-7160735-B2 Tagged microparticle compositions and methods MONOGRAM BIOSCIENCES, INC. (US) 2007-01-09 — — US disclosed
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