SCHEMBL9906229

SCHEMBL9906229

O=C(CSCCC(=O)ON1C(=O)CCC1=O)NCCOCCOCCNC(=O)c1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 2/20 0.51
▸ ALB P02768 2/20 0.47
▸ HTRA2 O43464 7/20 0.44
▸ HTRA1 Q92743 7/20 0.44
▸ ESR1 P03372 1/20 0.42
▸ DNASE1L3 Q13609 1/20 0.41
▸ PRMT1 Q99873 1/20 0.41
▸ BTK Q06187 1/20 0.41
▸ USP2 O75604 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9906192 0.96 ALB (0.49) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL9906326 0.96 FOLH1 (0.56) FOLH1ALBESR1BTKUSP2
SCHEMBL9906226 0.96 ALB (0.49) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL9906261 0.94 ALB (0.52) FOLH1ALBHTRA2HTRA1
SCHEMBL9906327 0.92 FOLH1 (0.52) FOLH1ALBESR1USP2L3MBTL1
SCHEMBL14427133 0.92 FOLH1 (0.46) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL1688099 0.91 FOLH1 (0.51) FOLH1ALBESR1USP2L3MBTL1
SCHEMBL9906325 0.90 FOLH1 (0.54) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL9906228 0.89 ALB (0.45) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL9906321 0.89 FOLH1 (0.55) FOLH1ALBHTRA2HTRA1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673399-B1 DETECTING AND PROFILING MOLECULAR COMPLEXES MONOGRAM BIOSCIENCES INC (US) 2017-04-05 — — EP disclosed
US-8198031-B2 Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening MONOGRAM BIOSCIENCES, INC. (US) 2012-06-12 — — US disclosed
EP-1540347-B1 DETECTING RECEPTOR OLIGOMERIZATION ACLARA BIOSCIENCES INC (US) 2009-09-09 — — EP disclosed
US-20090173631-A1 Single Cell Analysis of Membrane Molecules ACLARA BIOSCIENCES, INC. 2009-07-09 — — US disclosed
US-20090011432-A1 Detecting and Profiling Molecular Complexes MONOGRAM BIOSCIENCES, INC. (US) 2009-01-08 — — US disclosed
US-20080233602-A1 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. 2008-09-25 — — US disclosed
US-7402397-B2 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. (US) 2008-07-22 — — US disclosed
US-7160735-B2 Tagged microparticle compositions and methods MONOGRAM BIOSCIENCES, INC. (US) 2007-01-09 — — US disclosed
Send feedback