SCHEMBL9906261

SCHEMBL9906261

O=C(CSCCC(=O)ON1C(=O)CCC1=O)NCCCCCCCCCCNC(=O)c1ccc(C(=O)O)c(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 2/20 0.52
▸ FOLH1 Q04609 2/20 0.50
▸ HTRA2 O43464 8/20 0.50
▸ HTRA1 Q92743 8/20 0.50
▸ SLC5A2 P31639 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9906226 0.97 ALB (0.49) ALBFOLH1HTRA2HTRA1
SCHEMBL9906321 0.95 FOLH1 (0.55) ALBFOLH1HTRA2HTRA1SLC5A2
SCHEMBL9906192 0.95 ALB (0.49) ALBFOLH1HTRA2HTRA1SLC5A2
SCHEMBL9906325 0.95 FOLH1 (0.54) ALBFOLH1HTRA2HTRA1SLC5A2
SCHEMBL9906229 0.94 FOLH1 (0.51) ALBFOLH1HTRA2HTRA1
SCHEMBL1688099 0.92 FOLH1 (0.51) ALBFOLH1SLC5A2
SCHEMBL17010839 0.92 FOLH1 (0.45) ALBFOLH1HTRA2HTRA1SLC5A2
SCHEMBL14427154 0.92 FOLH1 (0.45) ALBFOLH1HTRA2HTRA1SLC5A2
SCHEMBL13073173 0.91 ALB (0.54) ALBFOLH1HTRA2HTRA1SLC5A2
SCHEMBL9906327 0.91 FOLH1 (0.52) ALBFOLH1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673399-B1 DETECTING AND PROFILING MOLECULAR COMPLEXES MONOGRAM BIOSCIENCES INC (US) 2017-04-05 — — EP disclosed
US-8198031-B2 Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening MONOGRAM BIOSCIENCES, INC. (US) 2012-06-12 — — US disclosed
EP-1540347-B1 DETECTING RECEPTOR OLIGOMERIZATION ACLARA BIOSCIENCES INC (US) 2009-09-09 — — EP disclosed
US-20090173631-A1 Single Cell Analysis of Membrane Molecules ACLARA BIOSCIENCES, INC. 2009-07-09 — — US disclosed
US-20080233602-A1 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. 2008-09-25 — — US disclosed
US-7402397-B2 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. (US) 2008-07-22 — — US disclosed
US-7255999-B2 Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide MONOGRAM BIOSCIENCES, INC. (US) 2007-08-14 — — US disclosed
US-7160735-B2 Tagged microparticle compositions and methods MONOGRAM BIOSCIENCES, INC. (US) 2007-01-09 — — US disclosed
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