Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 14/20 | 0.47 |
| ▸ | CA1 | P00915 | 12/20 | 0.47 |
| ▸ | CA2 | P00918 | 12/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23808967 | 0.89 | USP2 (0.60) | USP2L3MBTL1ESR1CA9CA1 | |
| SCHEMBL14619874 | 0.86 | USP2 (0.63) | USP2L3MBTL1ESR1CA9CA1 | |
| SCHEMBL1688096 | 0.86 | CA9 (0.52) | USP2L3MBTL1CA9CA1CA2 | |
| SCHEMBL29837449 | 0.86 | CA9 (0.52) | USP2L3MBTL1CA9CA1CA2 | |
| SCHEMBL13678665 | 0.84 | ESR1 (0.52) | USP2L3MBTL1ESR1CA9CA1 | |
| SCHEMBL19451947 | 0.84 | USP2 (0.62) | USP2L3MBTL1ESR1CA9CA1 | |
| SCHEMBL9906193 | 0.83 | CA9 (0.49) | USP2L3MBTL1CA9CA1CA2 | |
| SCHEMBL1688099 | 0.83 | FOLH1 (0.51) | USP2L3MBTL1ESR1CA9CA1 | |
| SCHEMBL20821271 | 0.83 | USP2 (0.55) | USP2L3MBTL1ESR1CA9CA1 | |
| SCHEMBL9906260 | 0.82 | DNASE1L3 (0.51) | USP2L3MBTL1CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673399-B1 | DETECTING AND PROFILING MOLECULAR COMPLEXES | MONOGRAM BIOSCIENCES INC (US) | 2017-04-05 | — | — | EP | disclosed |
| US-8198031-B2 | Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening | MONOGRAM BIOSCIENCES, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20090011432-A1 | Detecting and Profiling Molecular Complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-20080233602-A1 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. | 2008-09-25 | — | — | US | disclosed |
| US-7402397-B2 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| US-7255999-B2 | Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide | MONOGRAM BIOSCIENCES, INC. (US) | 2007-08-14 | — | — | US | disclosed |
| US-7217531-B2 | Multiplex analysis using membrane-bound sensitizers | MONOGRAM BIOSCIENCES (US) | 2007-05-15 | — | — | US | disclosed |
| US-7160735-B2 | Tagged microparticle compositions and methods | MONOGRAM BIOSCIENCES, INC. (US) | 2007-01-09 | — | — | US | disclosed |