SCHEMBL14427154

SCHEMBL14427154

Cc1cc(C(=O)NCCCCNC(=O)CSCCC(=O)ON2C(=O)CCC2=O)ccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 2/20 0.45
▸ ALB P02768 2/20 0.44
▸ HTRA2 O43464 7/20 0.42
▸ HTRA1 Q92743 7/20 0.42
▸ ESR1 P03372 1/20 0.40
▸ SLC5A2 P31639 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17010839 0.95 FOLH1 (0.45) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL14526054 0.93 FOLH1 (0.41) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL9906261 0.92 ALB (0.52) FOLH1ALBHTRA2HTRA1SLC5A2
SCHEMBL9906325 0.92 FOLH1 (0.54) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL9906321 0.91 FOLH1 (0.55) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL14427133 0.90 FOLH1 (0.46) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL9906226 0.90 ALB (0.49) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL1688099 0.89 FOLH1 (0.51) FOLH1ALBESR1SLC5A2
SCHEMBL9906192 0.88 ALB (0.49) FOLH1ALBHTRA2HTRA1ESR1
SCHEMBL9906327 0.87 FOLH1 (0.52) FOLH1ALBESR1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7255999-B2 Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide MONOGRAM BIOSCIENCES, INC. (US) 2007-08-14 — — US disclosed
US-7160735-B2 Tagged microparticle compositions and methods MONOGRAM BIOSCIENCES, INC. (US) 2007-01-09 — — US disclosed
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