Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 6/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906364 | 0.86 | CNR1 (0.43) | GRNSORT1KDM4ECNR1CNR2 | |
| SCHEMBL17066944 | 0.84 | LMNA (0.38) | KDM4ECNR1CNR2GAA | |
| SCHEMBL21232814 | 0.82 | GRN (0.35) | GRNSORT1KDM4ECNR1CNR2 | |
| SCHEMBL13114437 | 0.81 | CNR1 (0.41) | GRNSORT1KDM4ECNR1CNR2 | |
| SCHEMBL9908245 | 0.81 | MAPK14 (0.39) | GRNSORT1KDM4ECNR1CNR2 | |
| SCHEMBL12789841 | 0.81 | GRN (0.36) | GRNSORT1KDM4ECNR1CNR2 | |
| SCHEMBL12789845 | 0.80 | GRN (0.37) | GRNSORT1KDM4ECNR1CNR2 | |
| SCHEMBL12789850 | 0.80 | GRN (0.35) | GRNSORT1KDM4ECNR1CNR2 | |
| SCHEMBL12789852 | 0.80 | GRN (0.35) | GRNSORT1KDM4ECNR1CNR2 | |
| SCHEMBL13790795 | 0.79 | LMNA (0.39) | GRNSORT1KDM4ECNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198308-B2 | Chemical compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-20110059938-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059938-A1 | NEW CHEMICAL COMPOUNDS | CCNA1, CCNT1, MKI67 | GRN 1532/4885SORT1 3054/4885KDM4E 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.