Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.43 |
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | GRN | P28799 | 4/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906363 | 0.86 | GRN (0.39) | CNR1CNR2GRNSORT1KDM4E | |
| SCHEMBL13114437 | 0.85 | CNR1 (0.41) | CNR1CNR2GRNSORT1KDM4E | |
| SCHEMBL12789845 | 0.83 | GRN (0.37) | CNR1CNR2GRNSORT1KDM4E | |
| SCHEMBL14200450 | 0.80 | CNR1 (0.40) | CNR1CNR2ALDH1A1ADORA2AADORA2B | |
| SCHEMBL9908245 | 0.78 | MAPK14 (0.39) | CNR1CNR2GRNSORT1KDM4E | |
| SCHEMBL12789841 | 0.78 | GRN (0.36) | CNR1CNR2GRNSORT1KDM4E | |
| SCHEMBL12789850 | 0.77 | GRN (0.35) | CNR1CNR2GRNSORT1KDM4E | |
| SCHEMBL12789852 | 0.77 | GRN (0.35) | CNR1CNR2GRNSORT1KDM4E | |
| SCHEMBL15071315 | 0.77 | CNR1 (0.42) | CNR1CNR2GRNSORT1KDM4E | |
| SCHEMBL2737348 | 0.77 | ADORA2B (0.42) | CNR1CNR2KDM4EALDH1A1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198308-B2 | Chemical compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-20110059938-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059938-A1 | NEW CHEMICAL COMPOUNDS | CCNA1, CCNT1, MKI67 | CNR1 112/4885CNR2 395/4885GRN 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.