SCHEMBL9906502

SCHEMBL9906502

C=CC(=O)OCCCOc1ccc2cc(C(=O)Oc3ccc(OC(=O)c4ccc5cc(OCCCOC(=O)C=C)ccc5c4)c(-c4ccc(F)cc4)c3)ccc2c1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.37
NPC1 O15118 1/20 0.37
PTPN7 P35236 1/20 0.36
MEN1 O00255 2/20 0.36
POLB P06746 2/20 0.36
PPARG P37231 4/20 0.36
PPARD Q03181 3/20 0.36
PPARA Q07869 3/20 0.36
MAPT P10636 2/20 0.35
THRB P10828 1/20 0.34
BCL9 O00512 2/20 0.34
CTNNB1 P35222 2/20 0.34
LSS P48449 1/20 0.33
STAT5A P42229 1/20 0.33
STAT5B P51692 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12742945 0.91 PTPN7 (0.39) KMT2ANPC1PTPN7MEN1POLB
SCHEMBL9906504 0.88 PTPN11 (0.36) KMT2ANPC1MEN1PPARGMAPT
SCHEMBL9906505 0.88 THRB (0.42) KMT2AMEN1MAPTTHRBTSHR
SCHEMBL9906492 0.84 TSHR (0.39) KMT2AMEN1POLBPPARGPPARD
SCHEMBL16689215 0.83 THRB (0.39) KMT2ANPC1MEN1PPARGPPARD
SCHEMBL816363 0.82 PPARG (0.39) KMT2APPARGPPARDPPARAMAPT
SCHEMBL816055 0.82 ALDH1A1 (0.41) POLBMAPTTHRBLSSTSHR
SCHEMBL12975854 0.82 HTT (0.39) KMT2ANPC1MEN1POLBMAPT
SCHEMBL13041586 0.81 ALDH1A1 (0.40) KMT2AMEN1MAPTTHRBLSS
SCHEMBL12742946 0.81 KMT2A (0.40) KMT2ANPC1MEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197710-B2 Polymerizable compound and polymerizable composition ADEKA CORPORATION (JP) 2012-06-12 US disclosed
US-20100294990-A1 POLYMERIZABLE COMPOUND AND POLYMERIZABLE COMPOSITION ADEKA CORPORATION (JP) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100294990-A1 POLYMERIZABLE COMPOUND AND POLYMERIZABLE COMPOSITION PYM1, SCO2, ZYX KMT2A 1150/4885NPC1 2406/4885PTPN7 3485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.