Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10327448 | 1.00 | AOC3 (0.49) | AOC3MEN1KMT2AS1PR2S1PR1 | |
| SCHEMBL19391256 | 1.00 | AOC3 (0.49) | AOC3MEN1KMT2AS1PR2S1PR1 | |
| SCHEMBL8102586 | 0.98 | AOC3 (0.50) | AOC3MEN1KMT2AS1PR2S1PR1 | |
| SCHEMBL13670751 | 0.95 | AOC3 (0.45) | AOC3MEN1KMT2AS1PR2S1PR1 | |
| SCHEMBL18503058 | 0.92 | AOC3 (0.52) | AOC3MEN1KMT2ADRD3HTR7 | |
| SCHEMBL9622464 | 0.87 | MEN1 (0.45) | AOC3MEN1KMT2AS1PR2S1PR1 | |
| SCHEMBL906150 | 0.86 | AOC3 (0.53) | AOC3MEN1KMT2ASLC6A4SIGMAR1 | |
| SCHEMBL13262326 | 0.86 | AOC3 (0.53) | AOC3MEN1KMT2ASLC6A4SIGMAR1 | |
| SCHEMBL9622461 | 0.85 | MEN1 (0.41) | AOC3MEN1KMT2AS1PR2S1PR1 | |
| Hydrochloric Acid SCHEMBL9622457 | 0.84 | MEN1 (0.49) | AOC3MEN1KMT2AS1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198487-B2 | Method for lithium exchange reactions | LONZA AG (CH) | 2012-06-12 | — | — | US | disclosed |
| US-20100113839-A1 | METHOD FOR LITHIUM EXCHANGE REACTIONS | LONZA AG (CH) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113839-A1 | METHOD FOR LITHIUM EXCHANGE REACTIONS | SLC6A5, SLC6A9, SLC6A6 | AOC3 3223/4885MEN1 160/4885KMT2A 3114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.