Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13050748 | 0.91 | TSHR (0.45) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9906821 | 0.82 | TDP1 (0.33) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13320409 | 0.79 | LMNA (0.54) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4231270 | 0.76 | MAPT (0.49) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3048238 | 0.75 | TSHR (0.46) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9906805 | 0.75 | LMNA (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL18036991 | 0.73 | ALDH1A1 (0.43) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17101653 | 0.72 | LMNA (0.43) | HDAC1HDAC2SMN1; SMN2HPGDMAPT | |
| SCHEMBL22204622 | 0.72 | HDAC3 (0.44) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13107756 | 0.72 | TSHR (0.42) | TSHRSMN1; SMN2HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546488-B2 | Cleavable block copolymers, functionalized nanoporous thin films and related methods of preparation | UNIVERSITY OF MASSACHUSETTS (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120245244-A1 | Cleavable block copolymers, functionalized nanoporous thin films and related methods of preparation | NATIONAL SCIENCE FOUNDATION | 2012-09-27 | — | — | US | disclosed |
| US-8198368-B2 | Cleavable block copolymers, functionalized nanoporous thin films and related methods of preparation | UNIVERSITY OF MASSACHUSETTS (US) | 2012-06-12 | — | — | US | disclosed |
| US-20090105427-A1 | Cleavable Block Copolymers, Functionalized Nanoporous Thin Films and Related Methods of Preparation | UNIVERSITY OF MASSACHUSETTS | 2009-04-23 | — | — | US | disclosed |