Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231270 | 0.88 | MAPT (0.49) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13050748 | 0.87 | TSHR (0.45) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3048238 | 0.81 | TSHR (0.46) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22204622 | 0.80 | HDAC3 (0.44) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9906806 | 0.79 | TSHR (0.38) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22204623 | 0.78 | HDAC3 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13829103 | 0.77 | L3MBTL1 (0.44) | LMNATP53ALDH1A1GAAL3MBTL1 | |
| SCHEMBL22848076 | 0.77 | TSHR (0.50) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18036991 | 0.75 | ALDH1A1 (0.43) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2705058 | 0.75 | ALDH1A1 (0.52) | LMNATP53HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714075-B1 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-05-11 | — | — | US | disclosed |
| US-7666962-B2 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-02-23 | — | — | US | disclosed |
| US-7662986-B2 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-02-16 | — | — | US | disclosed |
| US-20080139836-A1 | Polymerization with living characteristics | LE TAM PHUONG | 2008-06-12 | — | — | US | disclosed |
| US-20080139764-A1 | Polymerization with living characteristics | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-06-12 | — | — | US | disclosed |
| US-7250479-B2 | Polymerization with living characteristics | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139836-A1 | Polymerization with living characteristics | UQCRB, MTR, UQCRC2 | LMNA 3210/4885TP53 4578/4885HDAC3 2448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.