SCHEMBL990770

SCHEMBL990770

Nc1cc(F)c(-c2ccccc2)cc1F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
HSD17B10 Q99714 2/20 0.48
SMARCA2 P51531 2/20 0.39
SMARCA4 P51532 2/20 0.39
PBRM1 Q86U86 2/20 0.39
BACE1 P56817 1/20 0.39
BRD4 O60885 2/20 0.39
PTGS1 P23219 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
PTGS2 P35354 2/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
FABP2 P12104 1/20 0.39
TSHR P16473 1/20 0.39
AKR1C4 P17516 1/20 0.39
ADRA2B P18089 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2C P28335 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21999626 0.91 ALDH1A1 (0.48) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1
SCHEMBL5402168 0.86 BACE1 (0.50) ALDH1A1HSD17B10BACE1PTGS1MEN1
SCHEMBL2542848 0.85 HSD17B10 (0.46) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1
SCHEMBL21087773 0.84 HSD17B10 (0.50) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1
SCHEMBL13385776 0.83 ALDH1A1 (0.42) ALDH1A1HSD17B10PTGS1MEN1KMT2A
SCHEMBL30296558 0.82 CSNK2A1 (0.44) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1
SCHEMBL26456968 0.82 CSNK2A1 (0.44) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1
SCHEMBL6573430 0.79 BACE1 (0.58) ALDH1A1HSD17B10SMARCA2SMARCA4PBRM1
SCHEMBL16890083 0.79 BACE1 (0.48) ALDH1A1HSD17B10BACE1PTGS1MEN1
SCHEMBL13385806 0.78 ALDH1A1 (0.48) ALDH1A1BRD4MEN1KMT2APDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9284486-B2 Blue fluorescent composition and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2016-03-15 US disclosed
US-9284486-B2 Blue fluorescent composition and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2016-03-15 US disclosed
US-20110006669-A1 Blue fluorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2011-01-13 US disclosed
US-20110006669-A1 Blue fluorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2011-01-13 US disclosed
US-20110006669-A1 Blue fluorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2011-01-13 US disclosed