Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990781 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HPGDGRM5GAACHRM5 | |
| SCHEMBL990808 | 0.90 | ALDH1A1 (0.49) | ALDH1A1HPGDGRM5KMT2AL3MBTL1 | |
| SCHEMBL990107 | 0.90 | ALDH1A1 (0.49) | ALDH1A1HPGDGRM5KMT2AL3MBTL1 | |
| SCHEMBL990050 | 0.89 | ALDH1A1 (0.48) | ALDH1A1HPGDGRM5KMT2AL3MBTL1 | |
| SCHEMBL991105 | 0.89 | ALDH1A1 (0.48) | ALDH1A1HPGDGRM5KMT2AL3MBTL1 | |
| SCHEMBL990890 | 0.84 | GRM5 (0.47) | GRM5CHRM5L3MBTL1 | |
| SCHEMBL990768 | 0.84 | GRM5 (0.47) | GRM5CHRM5L3MBTL1 | |
| SCHEMBL4880266 | 0.84 | GRM5 (0.53) | GRM5GAACHRM5KMT2AMEN1 | |
| SCHEMBL990045 | 0.83 | GRM5 (0.54) | ALDH1A1GRM5 | |
| SCHEMBL4507971 | 0.81 | GRM5 (0.44) | ALDH1A1HPGDGRM5KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272509-A1 | New Uses of metabotropic glutamate receptors | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |