Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990107 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HPGDGRM5TSHRUSP2 | |
| SCHEMBL991105 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HPGDGRM5L3MBTL1KMT2A | |
| SCHEMBL990050 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HPGDGRM5L3MBTL1KMT2A | |
| SCHEMBL990810 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HPGDGRM5L3MBTL1MEN1 | |
| SCHEMBL990781 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HPGDGRM5L3MBTL1MEN1 | |
| SCHEMBL991006 | 0.86 | GRM5 (0.46) | ALDH1A1HPGDGRM5TSHRL3MBTL1 | |
| SCHEMBL992693 | 0.86 | GRM5 (0.46) | ALDH1A1HPGDGRM5TSHRL3MBTL1 | |
| SCHEMBL990340 | 0.85 | L3MBTL1 (0.59) | GRM5L3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL992077 | 0.85 | GRM5 (0.44) | GRM5L3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL990212 | 0.85 | GRM5 (0.44) | GRM5L3MBTL1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272509-A1 | New Uses of metabotropic glutamate receptors | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |