Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10177655 | 1.00 | MMP2 (0.40) | MMP2MMP3MMP7MMP9MMP13 | |
| SCHEMBL14978137 | 1.00 | MMP2 (0.40) | MMP2MMP3MMP7MMP9MMP13 | |
| SCHEMBL16393116 | 0.91 | HDAC1 (0.38) | HDAC6SLC6A11SLC6A1NAMPTDPP4 | |
| SCHEMBL31534289 | 0.91 | HDAC1 (0.38) | HDAC6SLC6A11SLC6A1NAMPTDPP4 | |
| SCHEMBL10177664 | 0.91 | HDAC6 (0.40) | HDAC6SLC6A11SLC6A1NAMPTDPP4 | |
| SCHEMBL14977891 | 0.90 | SLC6A11 (0.42) | SLC6A11SLC6A1MEN1TP53CYP1A2 | |
| SCHEMBL10177713 | 0.90 | HDAC6 (0.39) | HDAC6SLC6A11SLC6A1NAMPTDPP4 | |
| SCHEMBL30209495 | 0.90 | HDAC6 (0.41) | HDAC6SLC6A11SLC6A1NAMPTSMN1; SMN2 | |
| SCHEMBL24383289 | 0.90 | SLC6A11 (0.41) | SLC6A11SLC6A1MEN1TP53CYP1A2 | |
| SCHEMBL9604443 | 0.90 | SLC6A11 (0.41) | SLC6A11SLC6A1MEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170107511-A1 | OLIGONUCLEOTIDE END CAPS | BANK OF AMERICA, N.A. | 2017-04-20 | — | — | US | disclosed |
| US-9512164-B2 | Oligonucleotide end caps | ALNYLAM PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-9512164-B2 | Oligonucleotide end caps | ALNYLAM PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20120142101-A1 | OLIGONUCLEOTIDE END CAPS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-07 | — | — | US | disclosed |