Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10177713 | 0.94 | HDAC6 (0.39) | HDAC6SLC6A1SLC6A11NAMPTSMN1; SMN2 | |
| SCHEMBL30209495 | 0.93 | HDAC6 (0.41) | HDAC6SLC6A1SLC6A11NAMPTSMN1; SMN2 | |
| SCHEMBL16681996 | 0.92 | HDAC6 (0.40) | HDAC6SLC6A1SLC6A11NAMPTSMN1; SMN2 | |
| SCHEMBL9908643 | 0.91 | MMP2 (0.40) | HDAC6SLC6A1SLC6A11NAMPTSMN1; SMN2 | |
| SCHEMBL14978137 | 0.91 | MMP2 (0.40) | HDAC6SLC6A1SLC6A11NAMPTSMN1; SMN2 | |
| SCHEMBL10177655 | 0.91 | MMP2 (0.40) | HDAC6SLC6A1SLC6A11NAMPTSMN1; SMN2 | |
| SCHEMBL24383294 | 0.91 | SLC6A11 (0.42) | SLC6A1SLC6A11CYP1A2CYP3A4 | |
| SCHEMBL9604514 | 0.91 | SLC6A11 (0.42) | SLC6A1SLC6A11CYP1A2CYP3A4 | |
| SCHEMBL16843276 | 0.91 | SLC6A11 (0.42) | SLC6A1SLC6A11CYP1A2CYP3A4 | |
| SCHEMBL17231722 | 0.91 | SLC6A11 (0.42) | SLC6A1SLC6A11CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106022-B2 | Carbohydrate conjugates as delivery agents for oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |