Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11992573 | 0.94 | SLC6A11 (0.34) | SLC6A1SLC6A11GAAMMP2MMP9 | |
| SCHEMBL12209383 | 0.92 | ALDH1A1 (0.34) | SLC6A1SLC6A11GAAMMP2MMP9 | |
| SCHEMBL11992545 | 0.92 | ALDH1A1 (0.34) | SLC6A1SLC6A11GAAMMP2MMP9 | |
| SCHEMBL15369129 | 0.90 | SLC6A1 (0.31) | SLC6A1SLC6A11MMP2MMP9HSD17B10 | |
| SCHEMBL16938709 | 0.86 | SLC6A1 (0.32) | SLC6A1SLC6A11 | |
| SCHEMBL16299839 | 0.86 | SLC6A11 (0.35) | SLC6A1SLC6A11MEN1KMT2A | |
| SCHEMBL2997021 | 0.85 | SLC6A11 (0.37) | SLC6A1SLC6A11MEN1KMT2A | |
| SCHEMBL26302696 | 0.85 | SLC6A11 (0.33) | SLC6A1SLC6A11MMP9MEN1KMT2A | |
| SCHEMBL21662396 | 0.85 | SLC6A11 (0.36) | SLC6A1SLC6A11MEN1KMT2A | |
| SCHEMBL11992564 | 0.84 | SLC6A1 (0.33) | SLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170107511-A1 | OLIGONUCLEOTIDE END CAPS | BANK OF AMERICA, N.A. | 2017-04-20 | — | — | US | disclosed |
| US-9512164-B2 | Oligonucleotide end caps | ALNYLAM PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-9512164-B2 | Oligonucleotide end caps | ALNYLAM PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20120142101-A1 | OLIGONUCLEOTIDE END CAPS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-07 | — | — | US | disclosed |