Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15128087 | 0.89 | KDM4E (0.41) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL16479797 | 0.83 | ALDH1A1 (0.64) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL2614484 | 0.83 | HTT (0.63) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL13389006 | 0.82 | HTT (0.42) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL16476940 | 0.79 | ALDH1A1 (0.37) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL14155640 | 0.78 | KDM4E (0.41) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL9906924 | 0.78 | KDM4E (0.35) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL12295133 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL4632645 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL13431156 | 0.77 | KDM4E (0.39) | ALDH1A1KDM4EHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118526517-A | Method for adsorbing enterogenic protein combined uremic toxin and precursor thereof | 南开大学 | 2024-08-23 | — | — | CN | claimed |
| CN-114773556-B | Green solid-phase synthesis method of covalent organic framework material | 耀科新材料(苏州)有限公司 | 2024-06-04 | — | — | CN | claimed |
| WO-2023124952-A1 | GREEN SOLID-PHASE SYNTHESIS METHOD FOR COVALENT ORGANIC FRAMEWORK MATERIAL | 张振杰 | 2023-07-06 | — | — | WO | claimed |
| CN-115010885-B | Preparation method of copper-based metal covalent organic framework and application of copper-based metal covalent organic framework in photocatalytic detoxification sulfur mustard simulant | 南昌大学 | 2023-06-27 | — | — | CN | claimed |
| CN-116284907-A | Sp (sp) 2 Carbon conjugated two-dimensional polymer film and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-06-23 | — | — | CN | claimed |
| CN-116239759-A | Conjugated two-dimensional polymer film and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-06-09 | — | — | CN | claimed |
| CN-115286757-B | Covalent organic framework material based on multi-nitrogen olefin connection and preparation method and application thereof | 中原工学院 | 2023-03-10 | — | — | CN | claimed |
| CN-115286757-A | Covalent organic framework material based on multi-nitrogen olefin connection and preparation method and application thereof | 中原工学院 | 2022-11-04 | — | — | CN | claimed |
| CN-115010885-A | Preparation method of copper-based metal covalent organic framework and application of copper-based metal covalent organic framework in photocatalysis detoxification sulfur mustard simulant | 南昌大学 | 2022-09-06 | — | — | CN | claimed |
| CN-114773556-A | Green solid-phase synthesis method of covalent organic framework material | 南开大学 | 2022-07-22 | — | — | CN | claimed |
| US-20250066528-A1 | Method for Synthesizing a Covalent Organic Framework Material | YOCOF MAT SUZHOU CO LTD (CN) | 2025-02-27 | — | — | US | disclosed |
| CN-118526517-A | Method for adsorbing enterogenic protein combined uremic toxin and precursor thereof | 南开大学 | 2024-08-23 | — | — | CN | disclosed |
| CN-114773556-B | Green solid-phase synthesis method of covalent organic framework material | 耀科新材料(苏州)有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-117844007-A | Sp (sp) 2 Preparation method of carbon conjugated two-dimensional polymer film | 中国科学院宁波材料技术与工程研究所 | 2024-04-09 | — | — | CN | disclosed |
| WO-2023124952-A1 | GREEN SOLID-PHASE SYNTHESIS METHOD FOR COVALENT ORGANIC FRAMEWORK MATERIAL | 张振杰 | 2023-07-06 | — | — | WO | disclosed |
| CN-114409862-A | 2,4, 6-trimethylpyridine-based vinyl-bridged two-dimensional covalent organic framework material and preparation method thereof | 上海交通大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-110591109-B | Carbon-carbon double bond bridged full-carbon skeleton two-dimensional conjugated organic framework material and preparation method thereof | 上海交通大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-110591109-A | Carbon-carbon double bond bridged full-carbon skeleton two-dimensional conjugated organic framework material and preparation method thereof | 上海交通大学 | 2019-12-20 | — | — | CN | disclosed |
| US-8198456-B2 | e.g. 1,4-dihydro-4-(1H-indazol-5-yl)-2,6-dimethyl-3,5-pyridinedicarbonitrile; c-Met tyrosine kinase inhibitor; antitumor agent; lung, liver, gastric and breast solid tumors; pancreatic cancer, glioma, and hepatocellular carcinoma | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-20080176833-A1 | DIHYDROPYRIDINE DERIVATIVES AS USEFUL AS PROTEIN KINASE INHIBITORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176833-A1 | DIHYDROPYRIDINE DERIVATIVES AS USEFUL AS PROTEIN KINASE INHIBITORS | MET, DMPK, RET | ALDH1A1 1341/4885KDM4E 1582/4885HTT 2390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.