SCHEMBL12295133

SCHEMBL12295133

Cc1c(C#N)c(C#N)c(C)c(C#N)c1C#N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
ATM Q13315 1/20 0.42
KDM4E B2RXH2 6/20 0.37
HPGD P15428 4/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
MAPT P10636 3/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
APOBEC3G Q9HC16 3/20 0.34
HTT P42858 2/20 0.34
ALOX15 P16050 2/20 0.34
HSD17B10 Q99714 2/20 0.34
GLA P06280 1/20 0.34
TSHR P16473 1/20 0.34
CYP2A6 P11509 1/20 0.33
HAVCR2 Q8TDQ0 1/20 0.33
GRM6 O15303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16747678 0.96 ALDH1A1 (0.42) ALDH1A1ATMKDM4EHPGDMEN1
SCHEMBL22736981 0.93 ALDH1A1 (0.41) ALDH1A1ATMKDM4EHPGDMEN1
SCHEMBL4632645 0.92 ALDH1A1 (0.44) ALDH1A1ATMKDM4EHPGDMEN1
SCHEMBL4240428 0.88 ATM (0.41) ALDH1A1ATMKDM4EHPGDMEN1
SCHEMBL31070867 0.88 ATM (0.41) ALDH1A1ATMKDM4EHPGDMEN1
SCHEMBL8958604 0.88 ATM (0.41) ALDH1A1ATMKDM4EHPGDMEN1
SCHEMBL15061128 0.87 ALDH1A1 (0.38) ALDH1A1ATMKDM4EHPGDMEN1
SCHEMBL11445487 0.85 ATM (0.39) ALDH1A1ATMKDM4EHPGDMEN1
SCHEMBL13387595 0.85 ALDH1A1 (0.41) ALDH1A1ATMKDM4EHPGDMEN1
SCHEMBL21018311 0.84 ALDH1A1 (0.37) ALDH1A1ATMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11365286-B2 Polyarylether-based polymer with side chain in methoxypolyethylene glycols structure, solid polymer electrolyte and preparation methods therefor DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2022-06-21 US disclosed
US-20220017695-A1 POLYARYLETHER-BASED POLYMER WITH SIDE CHAIN IN POLYETHYLENE GLYCOL STRUCTURE, SOLID POLYMER ELECTROLYTE AND PREPARATION METHODS THEREFOR DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2022-01-20 US disclosed
US-10005879-B2 Method for producing an organic semiconductor device BASF SE (DE) 2018-06-26 US disclosed
EP-2828903-B1 OPTOELECTRONIC DEVICES COMPRISING POLYMERIC BLENDS RAYNERGY TEK INC (TW) 2017-11-01 EP disclosed
EP-2810313-B1 METHOD FOR PRODUCING AN ORGANIC SEMICONDUCTOR DEVICE BASF SE (DE) 2017-06-14 EP disclosed
US-9312492-B2 Polymeric blends and related optoelectronic devices RAYNERGY TEK INC. (TW) 2016-04-12 US disclosed
US-20160072070-A1 POLYMERIC BLENDS AND RELATED OPTOELECTRONIC DEVICES POLYERA CORPORATION 2016-03-10 US disclosed
US-20150171332-A1 POLYMERIC BLENDS AND RELATED OPTOELECTRONIC DEVICES RAYNERGY TEK INC. (TW) 2015-06-18 US disclosed
US-20150144927-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY (JP) 2015-05-28 US disclosed
US-8927971-B2 Semiconducting compounds and devices incorporating same UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2015-01-06 US disclosed
US-20120264900-A1 THIENOCORONENE-IMIDE SEMICONDUCTING COMPOUNDS AND POLYMERS USINVEST LLC 2012-10-18 US disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed
WO-2011119374-A1 CONJUGATED POLYMERS AND DEVICES INCORPORATING SAME POLYERA CORPORATION (US) 2011-09-29 WO disclosed
WO-2011119446-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME POLYERA CORPORATION (US) 2011-09-29 WO disclosed
WO-2011117849-A1 THIENOCORONENE-IMIDE SEMICONDUCTING COMPOUNDS AND POLYMERS BASF SE (DE) 2011-09-29 WO disclosed
WO-2010117449-A2 SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2010-10-14 WO disclosed
WO-2010052287-A1 ORGANIC SEMICONDUCTING POLYMERS BASF SE (DE) 2010-05-14 WO disclosed
WO-2009098253-A9 NAPHTHALENE-IMIDE SEMICONDUCTOR POLYMERS BASF SE (DE) 2009-10-15 WO disclosed
WO-2009098250-A1 PERYLENE-IMIDE SEMICONDUCTOR POLYMERS BASF SE (DE) 2009-08-13 WO disclosed
WO-2009098253-A1 NAPHTHALENE-IMIDE SEMICONDUCTOR POLYMERS BASF SE (DE) 2009-08-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264900-A1 THIENOCORONENE-IMIDE SEMICONDUCTING COMPOUNDS AND POLYMERS TST, TPR, SLC19A2 ALDH1A1 4190/4885ATM 1999/4885KDM4E 2633/4885
US-20150144927-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE LEF1, CORO1A, CORO1C ALDH1A1 232/4885ATM 3044/4885KDM4E 3798/4885
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom MCCC2, AFF2, F13A1 ALDH1A1 181/4885ATM 3040/4885KDM4E 2650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.