Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTH | P32929 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | AOC2 | O75106 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131896 | 0.80 | — | — | |
| SCHEMBL1691078 | 0.78 | — | — | |
| SCHEMBL17119861 | 0.75 | — | — | |
| SCHEMBL20323218 | 0.75 | CTH (0.44) | MAPTCTHKDM4EGAARECQL | |
| SCHEMBL24136136 | 0.75 | — | — | |
| SCHEMBL9909109 | 0.73 | CTH (0.42) | MAPTPOLBCTHKDM4EGAA | |
| SCHEMBL204110 | 0.73 | — | — | |
| SCHEMBL15803698 | 0.73 | — | — | |
| SCHEMBL6055332 | 0.72 | — | — | |
| SCHEMBL2599790 | 0.71 | CTH (0.36) | MAPTCTHGAARECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790374-B2 | Aqueous cross-linking compositions and methods | COLUMBIA INSURANCE COMPANY (US) | 2017-10-17 | — | — | US | disclosed |
| EP-2576708-B1 | AQUEOUS CROSS-LINKING COMPOSITIONS AND METHODS | MOORE BENJAMIN & CO (US) | 2016-09-21 | — | — | EP | disclosed |
| US-9040617-B2 | Aqueous cross-linking compositions and methods | COLUMBIA INSURANCE COMPANY, INC. (US) | 2015-05-26 | — | — | US | disclosed |
| US-20140228509-A1 | Aqueous Cross-linking Compositions and Methods | COLUMBIA INSURANCE COMPANY (US) | 2014-08-14 | — | — | US | disclosed |
| WO-2013130248-A1 | AQUEOUS CROSS-LINKING COMPOSITIONS AND METHODS | BENJAMIN MOORE & CO. (US) | 2013-09-06 | — | — | WO | disclosed |
| US-20120142847-A1 | AQUEOUS CROSS-LINKING COMPOSITIONS AND METHODS | COLUMBIA INSURANCE COMPANY (US) | 2012-06-07 | — | — | US | disclosed |
| US-20100273924-A1 | CURABLE COMPOSITIONS HAVING LESS VOLATILIZATION | SIKA TECHNOLOGY AG (CH) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273924-A1 | CURABLE COMPOSITIONS HAVING LESS VOLATILIZATION | CA4, CTH, CA6 | MAPT 399/4885POLB 1743/4885CTH 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.