SCHEMBL2599790

SCHEMBL2599790

CC(C)=NNC(=O)N(C)C

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CTH P32929 1/20 0.36
ALDH1A1 P00352 3/20 0.33
TSHR P16473 3/20 0.33
NFKB1 P19838 1/20 0.33
THPO P40225 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 1/20 0.33
APEX1 P27695 1/20 0.33
PMP22 Q01453 1/20 0.33
GAA P10253 1/20 0.32
RECQL P46063 1/20 0.32
CHRNB2 P17787 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2599746 0.77 KDM4E (0.34) ALDH1A1MAPTGAACHRNB2CHRNB4
SCHEMBL2599770 0.73 CTH (0.37) CTHALDH1A1MAPTGAARECQL
SCHEMBL609663 0.72
SCHEMBL131896 0.71
SCHEMBL9909119 0.71 MAPT (0.44) CTHALDH1A1NFKB1MAPTGAA
SCHEMBL27111947 0.70
SCHEMBL2599780 0.70 ALDH1A1 (0.37) ALDH1A1MAPTGAA
SCHEMBL1691078 0.69
SCHEMBL18469661 0.69 KDM4E (0.38) CTHALDH1A1MAPTGAARECQL
SCHEMBL24136136 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2780410-B1 ALKYL OR DIALKYL-SEMICARBAZONES AS A HARDENERS FOR EPOXY RESIN ALZCHEM AG (DE) 2017-09-06 EP claimed
US-9499684-B2 Alkyl or dialkyl-semicarbazone as a hardener for epoxy resin ALZCHEM AG (DE) 2016-11-22 US claimed
US-20140308863-A1 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN ALZCHEM AG (DE) 2014-10-16 US claimed
EP-2780410-A2 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN AlzChem AG (DE) 2014-09-24 EP claimed
WO-2013072354-A2 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN ALZCHEM AG (DE) 2013-05-23 WO claimed
US-20130079488-A1 Semicarbazones as Accelerators for Curing Epoxy Resins ALZCHEM AG (DE) 2013-03-28 US claimed
EP-2571917-A1 SEMICARBAZONES AS ACCELERATORS FOR CURING EPOXY RESINS AlzChem AG (DE) 2013-03-27 EP claimed
WO-2011144659-A1 SEMICARBAZONES AS ACCELERATORS FOR CURING EPOXY RESINS ALZCHEM TROSTBERG GMBH (DE) 2011-11-24 WO claimed
EP-2780410-B1 ALKYL OR DIALKYL-SEMICARBAZONES AS A HARDENERS FOR EPOXY RESIN ALZCHEM AG (DE) 2017-09-06 EP disclosed
EP-2571917-B1 SEMICARBAZONES AS ACCELERATORS FOR CURING EPOXY RESINS ALZCHEM AG (DE) 2016-12-07 EP disclosed
US-9499684-B2 Alkyl or dialkyl-semicarbazone as a hardener for epoxy resin ALZCHEM AG (DE) 2016-11-22 US disclosed
US-9403976-B2 Semicarbazones as accelerators for curing epoxy resins ALZCHEM AG (DE) 2016-08-02 US disclosed
US-20160083575-A1 Semicarbazones as accelerators for curing epoxy resins ALZCHEM AG (DE) 2016-03-24 US disclosed
WO-2015113930-A1 LIQUID CURING COMPOSITION FOR CURING POLYMER RESINS (I) ALZCHEM AG (DE) 2015-08-06 WO disclosed
US-20140308863-A1 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN ALZCHEM AG (DE) 2014-10-16 US disclosed
EP-2780410-A2 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN AlzChem AG (DE) 2014-09-24 EP disclosed
WO-2013072354-A2 ALKYL OR DIALKYL-SEMICARBAZONE AS A HARDENER FOR EPOXY RESIN ALZCHEM AG (DE) 2013-05-23 WO disclosed
US-20130079488-A1 Semicarbazones as Accelerators for Curing Epoxy Resins ALZCHEM AG (DE) 2013-03-28 US disclosed
EP-2571917-A1 SEMICARBAZONES AS ACCELERATORS FOR CURING EPOXY RESINS AlzChem AG (DE) 2013-03-27 EP disclosed
WO-2011144659-A1 SEMICARBAZONES AS ACCELERATORS FOR CURING EPOXY RESINS ALZCHEM TROSTBERG GMBH (DE) 2011-11-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130079488-A1 Semicarbazones as Accelerators for Curing Epoxy Resins EP300, HDAC2, HDAC1 CTH 2523/4885ALDH1A1 48/4885TSHR 3527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.