Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | KDM5A | P29375 | 3/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.55 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM6B | O15054 | 1/20 | 0.55 |
| ▸ | TET3 | O43151 | 1/20 | 0.55 |
| ▸ | KDM4A | O75164 | 1/20 | 0.55 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.55 |
| ▸ | KDM5C | P41229 | 1/20 | 0.55 |
| ▸ | ASPH | Q12797 | 1/20 | 0.55 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.55 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.55 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.55 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.55 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.55 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.55 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30209742 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1KDM5AKDM4CKDM5B | |
| SCHEMBL12256869 | 0.85 | ALDH1A1 (0.73) | KDM4EALDH1A1KDM5AKDM4CKDM5B | |
| SCHEMBL8861151 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1KDM5AKDM4CKDM5B | |
| SCHEMBL30209724 | 0.80 | ALDH1A1 (0.67) | KDM4EALDH1A1KDM4CKDM3AMAPT | |
| SCHEMBL12591131 | 0.80 | ALDH1A1 (0.67) | KDM4EALDH1A1KDM4CKDM3AMAPT | |
| SCHEMBL9943692 | 0.80 | ALDH1A1 (0.67) | KDM4EALDH1A1KDM5AKDM4CKDM5B | |
| SCHEMBL2464624 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1MAPTSMN1; SMN2SIRT2 | |
| SCHEMBL14876436 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1KDM5AKDM4CKDM5B | |
| SCHEMBL29094918 | 0.77 | ALDH1A1 (0.62) | KDM4EALDH1A1KDM5AKDM4CKDM5B | |
| SCHEMBL2198354 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1KDM5AKDM4CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8591636-B2 | Plating catalyst and method | ROHM AND HAAS ELECTRONICS MATERIALS LLC (US) | 2013-11-26 | — | — | US | claimed |
| WO-2013090161-A1 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-20 | — | — | WO | claimed |
| US-20130150622-A1 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | US | claimed |
| US-20230233541-A1 | SUBSTITUTED BENZAMIDES AS MODULATORS OF TREX1 | CONSTELLATION PHARMACEUTICALS, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230233541-A1 | SUBSTITUTED BENZAMIDES AS MODULATORS OF TREX1 | CONSTELLATION PHARMACEUTICALS, INC. | 2023-07-27 | — | — | US | disclosed |
| EP-4157821-A1 | SUBSTITUTED BENZAMIDES AS MODULATORS OF TREX1 | Constellation Pharmaceuticals, Inc. (US) | 2023-04-05 | — | — | EP | disclosed |
| CN-115867535-A | Substituted benzamides as modulators of TREX1 | 星座制药公司 | 2023-03-28 | — | — | CN | disclosed |
| WO-2021243001-A1 | SUBSTITUTED BENZAMIDES AS MODULATORS OF TREX1 | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2021-12-02 | — | — | WO | disclosed |
| CN-106458880-B | Organic selenium compound, preparation method and its medicinal usage especially as antitumor agent | 特瑞海德公司 | 2019-09-10 | — | — | CN | disclosed |
| EP-2465974-B1 | Plating catalyst and method | ROHM & HAAS ELECT MAT (US) | 2018-11-28 | — | — | EP | disclosed |
| CN-103415507-B | As the 3-amino-pyridine class of GPBAR1 agonist | HOFFMAN-LA ROCHE LTD. (CH) | 2016-03-02 | — | — | CN | disclosed |
| CN-1149191-C | Azetidine derivatives, Preparation and medicines containing them | ���ĵ�˹ҩ��ɷ�����˾ | 2004-05-12 | — | — | CN | disclosed |
| US-20040086742-A1 | Organic light emitting materials and devices | UNIVERSAL DISPLAY CORPORATION | 2004-05-06 | — | — | US | disclosed |
| WO-2004016711-A1 | ORGANIC LIGHT EMITTING MATERIALS AND DEVICES | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-02-26 | — | — | WO | disclosed |
| US-6687266-B1 | Organic light emitting materials and devices | UNIVERSAL DISPLAY CORPORATION | 2004-02-03 | — | — | US | disclosed |
| CN-1082061-C | Cumarin and quinolinone derivatives for preparing liquid crystal orientation layers | ROLIC AG (CH) | 2002-04-03 | — | — | CN | disclosed |
| CN-1316991-A | Azetidine derivatives, preparation and medicines containing them | AVENTIS PHARMA SA (FR) | 2001-10-10 | — | — | CN | disclosed |
| CN-1242368-A | New imidazotriazolopyrimidines, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-01-26 | — | — | CN | disclosed |
| CN-1239949-A | Novel heterocyclic substituted benzamides and their use for the control of diseases | BASF AG (DE) | 1999-12-29 | — | — | CN | disclosed |
| CN-1159815-A | Cumarin and quinolinone derivatives for preparing liquid crystal orientation layers | HOFFMANN LA ROCHE (CH) | 1997-09-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233541-A1 | SUBSTITUTED BENZAMIDES AS MODULATORS OF TREX1 | TREH, BRIX1, GBA1 | KDM4E 2037/4885ALDH1A1 327/4885KDM5A 1879/4885 |
| US-20130150622-A1 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS | SLC6A2, SLC6A4, SLC6A6 | KDM4E 1955/4885ALDH1A1 891/4885KDM5A 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.