Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.56 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.56 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.56 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940480 | 0.80 | TSHR (0.63) | LMNAOR51E2SLC22A6TSHRNFKB1 | |
| SCHEMBL3961702 | 0.80 | TSHR (0.63) | LMNAOR51E2SLC22A6TSHRNFKB1 | |
| SCHEMBL14054474 | 0.77 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1TET2 | |
| SCHEMBL13466788 | 0.77 | TET2 (0.35) | TET2KDM2AKDM4AKDM4CTET3 | |
| SCHEMBL300998 | 0.77 | OR51E2 (0.52) | EGLN1TET2KDM2AKDM4AKDM4C | |
| SCHEMBL1333038 | 0.77 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1TET2 | |
| SCHEMBL10143323 | 0.77 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1TET2 | |
| Succinic Acid SCHEMBL21867134 | 0.75 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1KDM2A | |
| Succinic Acid SCHEMBL4269135 | 0.75 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1KDM2A | |
| Succinic Acid SCHEMBL3799615 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663801-B2 | Methods of producing four carbon molecules | INVISTA NORTH AMERICA S.A.R.L. (US) | 2017-05-30 | — | — | US | disclosed |
| US-9382556-B2 | Microorganisms for the production of adipic acid and other compounds | GENOMATICA, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| US-8778642-B2 | Biological synthesis of difunctional alkanes from carbohydrate feedstocks | CELEXION, LLC (US) | 2014-07-15 | — | — | US | disclosed |
| US-8778642-B2 | Biological synthesis of difunctional alkanes from carbohydrate feedstocks | CELEXION, LLC (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130210104-A1 | METHODS OF PRODUCING FOUR CARBON MOLECULES | INVISTA NORTH AMERICA S.A R.L. (US) | 2013-08-15 | — | — | US | disclosed |
| US-20120258504-A1 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES FROM CARBOHYDRATE FEEDSTOCKS | CELEXION, LLC (US) | 2012-10-11 | — | — | US | disclosed |
| US-20120258504-A1 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES FROM CARBOHYDRATE FEEDSTOCKS | CELEXION, LLC (US) | 2012-10-11 | — | — | US | disclosed |
| US-8192976-B2 | Biological synthesis of difunctional alkanes from carbohydrate feedstocks | CELEXION, LLC (US) | 2012-06-05 | — | — | US | disclosed |
| US-8192976-B2 | Biological synthesis of difunctional alkanes from carbohydrate feedstocks | CELEXION, LLC (US) | 2012-06-05 | — | — | US | disclosed |
| US-8088607-B2 | Microorganisms for the production of adipic acid and other compounds | GENOMATICA, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100330626-A1 | MICROORGANISMS FOR THE PRODUCTION OF ADIPIC ACID AND OTHER COMPOUNDS | GENOMATICA, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100151536-A1 | Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks | CELEXION, LLC | 2010-06-17 | — | — | US | disclosed |
| US-20100151536-A1 | Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks | CELEXION, LLC | 2010-06-17 | — | — | US | disclosed |