Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.52 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.35 |
| ▸ | KDM4A | O75164 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361798 | 0.78 | OR51E2 (0.79) | OR51E2MAPK1SLC13A3EGLN1HAO1 | |
| SCHEMBL9909687 | 0.77 | LMNA (0.56) | OR51E2MAPK1SLC13A3EGLN1TET2 | |
| SCHEMBL27857415 | 0.75 | OR51E2 (0.73) | OR51E2MAPK1SLC13A3EGLN1HAO1 | |
| SCHEMBL14262191 | 0.74 | OR51E2 (0.48) | OR51E2MAPK1SLC13A3EGLN1TET2 | |
| SCHEMBL13466788 | 0.72 | TET2 (0.35) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL11346087 | 0.70 | ALDH1A1 (0.48) | OR51E2MAPK1SLC13A3EGLN1TET2 | |
| SCHEMBL11457936 | 0.70 | TET2 (0.64) | OR51E2MAPK1SLC13A3EGLN1TET2 | |
| SCHEMBL28831276 | 0.70 | OR51E2 (0.43) | OR51E2MAPK1SLC13A3EGLN1TET2 | |
| Alpha-Ketoglutaric Acid SCHEMBL3776640 | 0.69 | EGLN1 (1.00) | OR51E2MAPK1SLC13A3EGLN1KDM2A | |
| Alpha-Ketoglutaric Acid SCHEMBL7400 | 0.69 | EGLN1 (1.00) | OR51E2MAPK1SLC13A3EGLN1KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858504-B1 | CARNITINE-CONTAINING PERITONEAL DIALYSIS SOLUTION HAVING IMPROVED BIOCOMPATIBILITY | SIGMA TAU IND FARMACEUTI (IT) | 2012-01-04 | — | — | EP | claimed |
| EP-1009377-A4 | MEDICAL USES OF PYRUVATES | UNIV CASE WESTERN RESERVE (US) | 2004-01-21 | — | — | EP | claimed |
| US-6086789-A | SKIN INJURIES | CASE WESTERN RESERVE UNIVERSITY (US) | 2000-07-11 | — | — | US | claimed |
| EP-1009377-A1 | MEDICAL USES OF PYRUVATES | Case Western Reserve University (US) | 2000-06-21 | — | — | EP | claimed |
| WO-1998051277-A1 | MEDICAL USES OF PYRUVATES | CASE WESTERN RESERVE UNIVERSITY (US) | 1998-11-19 | — | — | WO | claimed |
| EP-1392639-B1 | PYRUVATE DERIVATIVES | GALILEO LAB INC (US) | 2008-09-17 | — | — | EP | disclosed |
| EP-1392639-A4 | PYRUVATE DERIVATIVES | GALILEO LAB INC (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1392639-A1 | PYRUVATE DERIVATIVES | Galileo Laboratories, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1009377-A4 | MEDICAL USES OF PYRUVATES | UNIV CASE WESTERN RESERVE (US) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002090314-A1 | PYRUVATE DERIVATIVES | GALILEO LABORATORIES, INC. (US) | 2002-11-14 | — | — | WO | disclosed |
| US-6086789-A | SKIN INJURIES | CASE WESTERN RESERVE UNIVERSITY (US) | 2000-07-11 | — | — | US | disclosed |
| EP-1009377-A1 | MEDICAL USES OF PYRUVATES | Case Western Reserve University (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1998051277-A1 | MEDICAL USES OF PYRUVATES | CASE WESTERN RESERVE UNIVERSITY (US) | 1998-11-19 | — | — | WO | disclosed |
| US-4158057-A | ADMINISTERING A MIXTURE OF PYRUVATE AND DIHYDROXYACETONE | STANKO RONALD T | 1979-06-12 | — | — | US | disclosed |