SCHEMBL10143323

SCHEMBL10143323

CC(O)C(=O)CCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
EGLN1 Q9GZT9 3/20 0.50
ALKBH5 Q6P6C2 1/20 0.50
SUCNR1 Q9BXA5 1/20 0.50
SLC15A2 Q16348 1/20 0.46
TP53 P04637 1/20 0.45
GABRP O00591 2/20 0.44
GABRD O14764 2/20 0.44
GABRA1 P14867 2/20 0.44
GABRB1 P18505 2/20 0.44
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44
GABRA5 P31644 2/20 0.44
GABRA3 P34903 2/20 0.44
GABRA2 P47869 2/20 0.44
GABRB2 P47870 2/20 0.44
GABRA4 P48169 2/20 0.44
GABRE P78334 2/20 0.44
GABRA6 Q16445 2/20 0.44
GABRG1 Q8N1C3 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL935212 0.82 TP53 (0.69) LMNAEGLN1ALKBH5SUCNR1SLC15A2
Succinic Acid SCHEMBL15949792 0.82 TP53 (0.69) LMNAEGLN1ALKBH5SUCNR1SLC15A2
Succinic Acid SCHEMBL21081056 0.82 LMNA (0.64) LMNAEGLN1ALKBH5SUCNR1SLC15A2
Succinic Acid SCHEMBL27463001 0.82 LMNA (0.64) LMNAEGLN1ALKBH5SUCNR1SLC15A2
Succinic Acid SCHEMBL4366411 0.80 TP53 (0.65) LMNAEGLN1ALKBH5SUCNR1SLC15A2
Succinic Acid SCHEMBL8157901 0.80 TP53 (0.65) LMNAEGLN1ALKBH5SUCNR1SLC15A2
Succinic Acid SCHEMBL8148316 0.80 TP53 (0.65) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL463465 0.80 EGLN1 (0.53) LMNAEGLN1ALKBH5SUCNR1SLC15A2
Succinic Acid SCHEMBL11016716 0.79 LMNA (0.60) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL21679771 0.79 EGLN1 (0.45) LMNAEGLN1ALKBH5SUCNR1SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120309062-A1 MICROORGANISMS FOR THE PRODUCTION OF ADIPIC ACID AND OTHER COMPOUNDS GENOMATICA, INC. (US) 2012-12-06 US disclosed
US-20120046498-A1 METHOD FOR PRODUCING POLYHYDRIC PHENOL MITSUI CHEMICALS, INC. (JP) 2012-02-23 US disclosed
US-20120046498-A1 METHOD FOR PRODUCING POLYHYDRIC PHENOL MITSUI CHEMICALS, INC. (JP) 2012-02-23 US disclosed
US-4902512-A Rhamnolipid liposomes DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY AND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046498-A1 METHOD FOR PRODUCING POLYHYDRIC PHENOL HPD, HAAO, SCO2 LMNA 3810/4885EGLN1 474/4885ALKBH5 372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.