Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9910358 | 0.81 | TSHR (0.52) | TSHRALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL27627561 | 0.81 | TSHR (0.52) | TSHRALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL22474643 | 0.75 | GAA (0.35) | TSHRALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL11896194 | 0.75 | TSHR (0.54) | TSHRALDH1A1LMNAKDM4EKMT2A | |
| Dimethyl Succinate SCHEMBL11848625 | 0.72 | TSHR (0.81) | TSHRALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL4494873 | 0.71 | TSHR (0.62) | TSHRALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL280474 | 0.70 | TSHR (0.56) | TSHRALDH1A1LMNAKDM4EKMT2A | |
| Dimethyl Succinate SCHEMBL28185979 | 0.70 | TSHR (0.87) | TSHRALDH1A1LMNAKDM4EKMT2A | |
| Dimethyl Succinate SCHEMBL28054469 | 0.69 | TSHR (1.00) | TSHRALDH1A1LMNAKDM4EKMT2A | |
| Dimethyl Succinate SCHEMBL10213 | 0.69 | TSHR (1.00) | TSHRALDH1A1LMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120258504-A1 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES FROM CARBOHYDRATE FEEDSTOCKS | CELEXION, LLC (US) | 2012-10-11 | — | — | US | disclosed |
| US-20120164702-A1 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES FROM CARBOHYDRATE FEEDSTOCKS | CELEXION, LLC (US) | 2012-06-28 | — | — | US | disclosed |
| US-8133704-B2 | Biological synthesis of difunctional alkanes from carbohydrate feedstocks | CELEXION, LLC (US) | 2012-03-13 | — | — | US | disclosed |
| US-20110171696-A1 | Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks | CELEXION, LLC (US) | 2011-07-14 | — | — | US | disclosed |