SCHEMBL991131

SCHEMBL991131

O=C1CCCCC(C(=O)c2cccc(C(=O)C3CCCCC(=O)N3)c2)N1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.44
MME P08473 6/20 0.38
ACE P12821 4/20 0.38
ECE1 P42892 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KMO O15229 1/20 0.36
ALOX5 P09917 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ABL1 P00519 1/20 0.35
PARP1 P09874 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9621799 0.98 MCL1 (0.43) MCL1MMEACEECE1MEN1
SCHEMBL7721046 0.90 ABL1 (0.38) MCL1MMEACEECE1MEN1
SCHEMBL38099 0.90 L3MBTL1 (0.48) MEN1KMT2AKDM4EALDH1A1PARP1
SCHEMBL8014971 0.89 MCL1 (0.57) MCL1MMEACEMEN1KMT2A
SCHEMBL38409 0.89 MCL1 (0.57) MCL1MMEACEMEN1KMT2A
SCHEMBL8645790 0.88 MCL1 (0.55) MCL1MMEACEMEN1KMT2A
SCHEMBL993051 0.87 MCL1 (0.45) MCL1MMEACEMEN1KMT2A
SCHEMBL7685839 0.87 CES2 (0.47) MEN1KMT2ASMN1; SMN2ALOX5KDM4E
SCHEMBL7684693 0.86 POLB (0.48) MEN1KMT2AALDH1A1
SCHEMBL8529217 0.85 L3MBTL1 (0.46) KDM4EPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117866226-A Amino-functionalized magnetic nanoparticle, and preparation method and application thereof 中国检验检疫科学研究院 2024-04-12 CN claimed
US-20220372221-A1 Process for Preparing Polyamide by Anionic Polymerization and Polyamide Prepared Thereby HANWHA SOLUTIONS CORPORAION (KR) 2022-11-24 US claimed
EP-4071198-A1 METHOD FOR PRODUCING POLYAMIDE THROUGH ANIONIC POLYMERIZATION, AND POLYAMIDE PREPARED THEREBY Hanwha Solutions Corporation (KR) 2022-10-12 EP claimed
WO-2022169155-A1 POLYAMIDE HYBRID RESIN COMPOSITION, AND LIGHTWEIGHT AND HIGH-STRENGTH MOLDED PRODUCT MANUFACTURED THEREFROM 엘지전자 주식회사 2022-08-11 WO claimed
CN-114761465-A Method for producing polyamides by anionic polymerization and polyamides produced thereby 韩华思路信株式会社 2022-07-15 CN claimed
WO-2021112495-A1 METHOD FOR PRODUCING POLYAMIDE THROUGH ANIONIC POLYMERIZATION, AND POLYAMIDE PREPARED THEREBY 한화솔루션 주식회사 2021-06-10 WO claimed
EP-2731996-B1 USE OF A POLYAMIDE CHAIN EXTENDING COMPOUND AS A STABILIZING AGENT RHODIA OPERATIONS (FR) 2018-04-04 EP claimed
US-9068101-B2 Sizing compositions and sized products for thermoplastic composites JOHNS MANVILLE (US) 2015-06-30 US claimed
US-8927651-B2 High-viscosity polyamide composition RHODIA OPERATIONS (FR) 2015-01-06 US claimed
US-20140296377-A1 SIZING COMPOSITIONS AND SIZED PRODUCTS FOR THERMOPLASTIC COMPOSITES JOHNS MANVILLE 2014-10-02 US claimed
US-4369222-A Metal-thermoplastic-metal laminates MONSANTO COMPANY (US) 1983-01-18 US claimed
US-4346200-A Thermoplastic polyamide compositions MONSANTO COMPANY (US) 1982-08-24 US claimed
EP-0013146-B1 METAL-THERMOPLASTIC-METAL LAMINATES AND A PROCESS FOR THE PREPARATION OF SUCH LAMINATES MONSANTO COMPANY (US) 1982-01-20 EP claimed
US-RE30371-E POLYESTERAMIDES FROM ACYLLACTAMS AND ALCOHOLS, METAL ANIONIC CATALYSTS MONSANTO COMPANY (US) 1980-08-12 US claimed
EP-0013146-A1 Metal-thermoplastic-metal laminates and a process for the preparation of such laminates MONSANTO COMPANY (US) 1980-07-09 EP claimed
US-4119679-A POLYESTERS, CURING AGENTS, EPOXY RESIN HITACHI CHEMICAL COMPANY, LTD. (JP) 1978-10-10 US claimed
US-4034015-A LACTAM-POLYOL-POLYACYL LACTAM OR LACTAM-POLYOL-ACYL POLYLACTAM, BLOCK POLYMERS MONSANTO COMPANY (US) 1977-07-05 US claimed
US-4031164-A LACTAM, POLYOL, POLYACYL LACTAM, CATALYST MONSANTO COMPANY (US) 1977-06-21 US claimed
US-4022955-A POWDER PAINTS HITACHI CHEMICAL COMPANY, LTD. (JA) 1977-05-10 US claimed
US-3965075-A POLYAMIDEESTERS FROM N-ACYLLACTAMS AND ALCOHOLS; TERT-AMINE OR ORGANOMETALLIC CATALYST MONSANTO COMPANY 1976-06-22 US claimed