Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.30 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911944 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL9911940 | 0.78 | TDP1 (0.37) | SMN1; SMN2TSHRGRNSORT1 | |
| SCHEMBL4144659 | 0.74 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL13329286 | 0.73 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2TSHRGRNSORT1 | |
| SCHEMBL7372261 | 0.72 | TSHR (0.37) | TSHR | |
| SCHEMBL9514833 | 0.72 | TSHR (0.37) | TSHR | |
| SCHEMBL15847388 | 0.72 | TSHR (0.37) | TSHR | |
| SCHEMBL14870828 | 0.71 | ESRRB (0.41) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL26625811 | 0.71 | ESRRB (0.41) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL13778536 | 0.71 | ABCB1 (0.37) | ALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952061-B2 | Methods and compounds regulating the erythroid response to iron deficiency | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130072428-A1 | Methods and Compounds Regulating the Erythroid Response to Iron Deficiency | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2013-03-21 | — | — | US | disclosed |
| US-20120142590-A1 | Methods and Compounds Regulating the Erythroid Response to Iron Deficiency | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142590-A1 | Methods and Compounds Regulating the Erythroid Response to Iron Deficiency | MCL1, FECH, MPL | ALDH1A1 1032/4885SMN1; SMN2 4522/4885TSHR 3244/4885 |
| US-20130072428-A1 | Methods and Compounds Regulating the Erythroid Response to Iron Deficiency | HIF1AN, IDH2, IDH3B | ALDH1A1 445/4885SMN1; SMN2 4453/4885TSHR 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.