Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17589207 | 0.81 | BRPF1 (0.34) | RAB9ASMN1; SMN2GAAALDH1A1BRPF1 | |
| SCHEMBL17494888 | 0.78 | RAB9A (0.44) | RAB9ASMN1; SMN2GAANPC1LMNA | |
| SCHEMBL21479586 | 0.77 | RAB9A (0.40) | RAB9ASMN1; SMN2GAANPC1LMNA | |
| SCHEMBL12147772 | 0.75 | RAB9A (0.36) | RAB9ASMN1; SMN2GAANPC1LMNA | |
| SCHEMBL17494864 | 0.75 | RAB9A (0.56) | RAB9ASMN1; SMN2GAANPC1LMNA | |
| SCHEMBL5030822 | 0.75 | RAB9A (0.42) | RAB9ASMN1; SMN2GAANPC1LMNA | |
| SCHEMBL3051505 | 0.73 | RAB9A (0.48) | RAB9ASMN1; SMN2GAANPC1LMNA | |
| SCHEMBL13680580 | 0.73 | RAB9A (0.39) | RAB9ASMN1; SMN2GAANPC1LMNA | |
| SCHEMBL3056330 | 0.72 | LMNA (0.54) | RAB9ASMN1; SMN2GAANPC1LMNA | |
| SCHEMBL3052229 | 0.72 | RAB9A (0.47) | RAB9ASMN1; SMN2GAANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220247-A1 | LRRK2 INHIBITORS | INTERLINE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-8648075-B2 | Substituted pyrido[2,3-b]pyrazines and an agrochemical composition thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| US-8648075-B2 | Substituted pyrido[2,3-b]pyrazines and an agrochemical composition thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| EP-2394995-B1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-20130137577-A1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-05-30 | — | — | US | disclosed |
| US-20130137577-A1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-05-30 | — | — | US | disclosed |
| US-8389523-B2 | Substituted quinoxaline and an agrochemical composition thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-03-05 | — | — | US | disclosed |
| US-8389523-B2 | Substituted quinoxaline and an agrochemical composition thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-03-05 | — | — | US | disclosed |
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| EP-2174934-B1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2012-06-06 | — | — | EP | disclosed |
| EP-2394995-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | Kumiai Chemical Industry CO., LTD. (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| WO-2010089993-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | クミアイ化学工業株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |
| US-20100197674-A1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20100197674-A1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| EP-2174934-A1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | CBR3, CBR1, CHRM1 | RAB9A 3900/4885SMN1; SMN2 2712/4885GAA 4099/4885 |
| US-20130137577-A1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | CBR3, CBR1, DDT | RAB9A 1771/4885SMN1; SMN2 3580/4885GAA 3541/4885 |
| US-20100197674-A1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | CBR3, CBR1, DDT | RAB9A 1771/4885SMN1; SMN2 3580/4885GAA 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.