Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 8/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22863319 | 0.99 | NAALAD2 (0.63) | NAALAD2FTOJAK2NQO1TTR | |
| SCHEMBL15045059 | 0.93 | FTO (0.61) | NAALAD2FTOJAK2NQO1TTR | |
| SCHEMBL12754623 | 0.93 | FTO (0.65) | NAALAD2FTOJAK2NQO1TTR | |
| SCHEMBL18872864 | 0.92 | FTO (0.65) | NAALAD2FTOJAK2NQO1TTR | |
| SCHEMBL29353892 | 0.89 | FTO (0.63) | NAALAD2FTOJAK2NQO1TTR | |
| SCHEMBL991216 | 0.89 | FTO (0.63) | NAALAD2FTOJAK2NQO1TTR | |
| SCHEMBL15744221 | 0.88 | FTO (0.64) | NAALAD2FTOJAK2NQO1TTR | |
| SCHEMBL20729848 | 0.88 | FTO (0.66) | NAALAD2FTOJAK2NQO1TTR | |
| SCHEMBL25711649 | 0.88 | NAALAD2 (0.60) | NAALAD2FTOJAK2NQO1TTR | |
| SCHEMBL16602999 | 0.87 | NAALAD2 (0.60) | NAALAD2FTOJAK2NQO1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681821-A | DETECTING PROTEASE IN CELLS | GEORGIA TECH RESEARCH CORP. (US) | 1997-10-28 | — | — | US | disclosed |