SCHEMBL991228

SCHEMBL991228

CNCCOCCCN(C)C

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.50
CARM1 Q86X55 1/20 0.50
PRMT6 Q96LA8 1/20 0.50
PRMT1 Q99873 1/20 0.50
PRMT8 Q9NR22 1/20 0.50
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HRH3 Q9Y5N1 3/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HRH1 P35367 1/20 0.33
LSS P48449 1/20 0.32
DNM1 Q05193 3/20 0.32
HTR1B P28222 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16806585 0.91 PRMT3 (0.46) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL12397048 0.91 PRMT3 (0.50) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL14579613 0.89 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL14579618 0.89 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL737040 0.86 PRMT3 (0.55) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL16381873 0.84 PRMT3 (0.52) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL12397038 0.84 PRMT3 (0.52) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL3404460 0.84 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL530011 0.83 ALDH1A1 (0.53) ALDH1A1TSHRKDM4ESMN1; SMN2HRH3
SCHEMBL15003875 0.82 PRMT3 (0.50) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200255577-A1 PROCESS FOR PREPARING POLYURETHNE FOAMS RHODIA OPERATIONS (FR) 2020-08-13 US disclosed
EP-2454304-A2 FORMAMIDE-CONTAINING REACTIVE SYSTEMS Bayer MaterialScience AG (DE) 2012-05-23 EP disclosed
WO-2011006607-A2 FORMAMIDE-CONTAINING REACTIVE SYSTEMS BAYER MATERIALSCIENCE AG (DE) 2011-01-20 WO disclosed