Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.55 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12397038 | 0.98 | PRMT3 (0.52) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL16381873 | 0.98 | PRMT3 (0.52) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL769793 | 0.93 | PRMT3 (0.48) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL991228 | 0.86 | PRMT3 (0.50) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL15003875 | 0.86 | PRMT3 (0.50) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL23207496 | 0.85 | PRMT3 (0.42) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL19914570 | 0.84 | PRMT3 (0.48) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25479584 | 0.84 | PRMT3 (0.54) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL16806585 | 0.82 | PRMT3 (0.46) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL5932834 | 0.82 | CYP2C9 (0.42) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250385-A1 | PRODUCTION OF POLYURETHANE OR POLYISOCYANURATE FOAM | EVONIK OPERATIONS GMBH (DE) | 2025-08-07 | — | — | US | claimed |
| EP-4596596-A1 | PRODUCTION OF POLYURETHANE OR POLYISOCYANURATE FOAM | Evonik Operations GmbH (DE) | 2025-08-06 | — | — | EP | claimed |
| WO-2024022833-A1 | METHOD FOR PREPARING FLEXIBLE SLABSTOCK POLYURETHANE FOAM | EVONIK OPERATIONS GMBH (DE) | 2024-02-01 | — | — | WO | claimed |
| EP-4240719-A1 | METHOD FOR PRODUCING SECONDARY AND TERTIARY AMINES | Huntsman Petrochemical LLC (US) | 2023-09-13 | — | — | EP | claimed |
| CN-116390907-A | Process for producing secondary and tertiary amines | 亨斯迈石油化学有限责任公司 | 2023-07-04 | — | — | CN | claimed |
| CN-111205192-B | Preparation method of N, N, N' -trimethyl bis (aminoethyl) ether | 新典化学材料(上海)有限公司(CN) | 2023-01-13 | — | — | CN | claimed |
| WO-2022098940-A1 | METHOD FOR PRODUCING SECONDARY AND TERTIARY AMINES | HUNTSMAN PETROCHEMICAL LLC (US) | 2022-05-12 | — | — | WO | claimed |
| EP-1878492-B2 | N,N,N'-Trimethyl-bis-(aminoethyl) ether and its derviatives as catalysts for polyurethanes | EVONIK DEGUSSA GMBH (DE) | 2018-05-23 | — | — | EP | claimed |
| EP-2160425-B1 | REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM | HUNTSMAN PETROCHEMICAL LLC (US) | 2012-11-07 | — | — | EP | claimed |
| US-20120149794-A1 | N,N,N'-Trimethyl-Bis-(Aminoethyl) Ether and its Derivatives as Catalysts for Polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2012-06-14 | — | — | US | claimed |
| US-8138378-B2 | separation of a first amine having a tertiary amine group and a secondary amine group such as N,N,N'-trimethylbis(aminoethyl)ether from a di-tertiary amine by forming an enamine; end use as reactive catalyst for low odor, lower VOC urethane foams | HUNTSMAN PETROCHEMICAL LLC (US) | 2012-03-20 | — | — | US | claimed |
| JP-2010530436-A | — | — | 2010-09-09 | — | — | JP | claimed |
| US-20100179297-A1 | REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM | HUNTSMAN PETRICHEMICAL LLC (US) | 2010-07-15 | — | — | US | claimed |
| US-20100130715-A1 | REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM | HUNTSMAN PETROCHEMICAL LLC (US) | 2010-05-27 | — | — | US | claimed |
| EP-2162480-A1 | REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM | Huntsman Petrochemical LLC (US) | 2010-03-17 | — | — | EP | claimed |
| EP-2160425-A1 | REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM | Huntsman Petrochemical LLC (US) | 2010-03-10 | — | — | EP | claimed |
| WO-2008157153-A1 | REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM | HUNTSMAN PETROCHEMICAL CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |
| WO-2008157151-A1 | REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM | HUNTSMAN PETROCHEMICAL CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |
| US-20080015273-A1 | N,N,N,'-trimethyl-bis-(aminoethyl) ether and its derivatives as catalysts for polyurethanes | EVONIK OPERATIONS GMBH (DE) | 2008-01-17 | — | — | US | claimed |
| EP-1878492-A2 | N,N,N'-Trimethyl-bis-(aminoethyl) ether and its derviatives as catalysts for polyurethanes | Air Products and Chemicals, Inc. (US) | 2008-01-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149794-A1 | N,N,N'-Trimethyl-Bis-(Aminoethyl) Ether and its Derivatives as Catalysts for Polyurethanes | GNE, PARN, GNMT | PRMT3 64/4885CARM1 275/4885PRMT6 195/4885 |
| US-20250250385-A1 | PRODUCTION OF POLYURETHANE OR POLYISOCYANURATE FOAM | PUF60, PARN, SLC39A11 | PRMT3 1205/4885CARM1 1861/4885PRMT6 2040/4885 |
| US-20100130715-A1 | REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM | PNMT, ALKBH3, ALKBH1 | PRMT3 14/4885CARM1 59/4885PRMT6 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.