SCHEMBL737040

SCHEMBL737040

CNCCOCCN(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.55
CARM1 Q86X55 1/20 0.55
PRMT6 Q96LA8 1/20 0.55
PRMT1 Q99873 1/20 0.55
PRMT8 Q9NR22 1/20 0.55
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
USP2 O75604 1/20 0.39
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRM3 P20309 1/20 0.33
CHRNA4 P43681 1/20 0.33
OPRK1 P41145 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12397038 0.98 PRMT3 (0.52) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL16381873 0.98 PRMT3 (0.52) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL769793 0.93 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL991228 0.86 PRMT3 (0.50) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL15003875 0.86 PRMT3 (0.50) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL23207496 0.85 PRMT3 (0.42) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL19914570 0.84 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL25479584 0.84 PRMT3 (0.54) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL16806585 0.82 PRMT3 (0.46) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL5932834 0.82 CYP2C9 (0.42) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250385-A1 PRODUCTION OF POLYURETHANE OR POLYISOCYANURATE FOAM EVONIK OPERATIONS GMBH (DE) 2025-08-07 US claimed
EP-4596596-A1 PRODUCTION OF POLYURETHANE OR POLYISOCYANURATE FOAM Evonik Operations GmbH (DE) 2025-08-06 EP claimed
WO-2024022833-A1 METHOD FOR PREPARING FLEXIBLE SLABSTOCK POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2024-02-01 WO claimed
EP-4240719-A1 METHOD FOR PRODUCING SECONDARY AND TERTIARY AMINES Huntsman Petrochemical LLC (US) 2023-09-13 EP claimed
CN-116390907-A Process for producing secondary and tertiary amines 亨斯迈石油化学有限责任公司 2023-07-04 CN claimed
CN-111205192-B Preparation method of N, N, N' -trimethyl bis (aminoethyl) ether 新典化学材料(上海)有限公司(CN) 2023-01-13 CN claimed
WO-2022098940-A1 METHOD FOR PRODUCING SECONDARY AND TERTIARY AMINES HUNTSMAN PETROCHEMICAL LLC (US) 2022-05-12 WO claimed
EP-1878492-B2 N,N,N'-Trimethyl-bis-(aminoethyl) ether and its derviatives as catalysts for polyurethanes EVONIK DEGUSSA GMBH (DE) 2018-05-23 EP claimed
EP-2160425-B1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM HUNTSMAN PETROCHEMICAL LLC (US) 2012-11-07 EP claimed
US-20120149794-A1 N,N,N'-Trimethyl-Bis-(Aminoethyl) Ether and its Derivatives as Catalysts for Polyurethanes AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-06-14 US claimed
US-8138378-B2 separation of a first amine having a tertiary amine group and a secondary amine group such as N,N,N'-trimethylbis(aminoethyl)ether from a di-tertiary amine by forming an enamine; end use as reactive catalyst for low odor, lower VOC urethane foams HUNTSMAN PETROCHEMICAL LLC (US) 2012-03-20 US claimed
JP-2010530436-A 2010-09-09 JP claimed
US-20100179297-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM HUNTSMAN PETRICHEMICAL LLC (US) 2010-07-15 US claimed
US-20100130715-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM HUNTSMAN PETROCHEMICAL LLC (US) 2010-05-27 US claimed
EP-2162480-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM Huntsman Petrochemical LLC (US) 2010-03-17 EP claimed
EP-2160425-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM Huntsman Petrochemical LLC (US) 2010-03-10 EP claimed
WO-2008157153-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM HUNTSMAN PETROCHEMICAL CORPORATION (US) 2008-12-24 WO claimed
WO-2008157151-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM HUNTSMAN PETROCHEMICAL CORPORATION (US) 2008-12-24 WO claimed
US-20080015273-A1 N,N,N,'-trimethyl-bis-(aminoethyl) ether and its derivatives as catalysts for polyurethanes EVONIK OPERATIONS GMBH (DE) 2008-01-17 US claimed
EP-1878492-A2 N,N,N'-Trimethyl-bis-(aminoethyl) ether and its derviatives as catalysts for polyurethanes Air Products and Chemicals, Inc. (US) 2008-01-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149794-A1 N,N,N'-Trimethyl-Bis-(Aminoethyl) Ether and its Derivatives as Catalysts for Polyurethanes GNE, PARN, GNMT PRMT3 64/4885CARM1 275/4885PRMT6 195/4885
US-20250250385-A1 PRODUCTION OF POLYURETHANE OR POLYISOCYANURATE FOAM PUF60, PARN, SLC39A11 PRMT3 1205/4885CARM1 1861/4885PRMT6 2040/4885
US-20100130715-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE FOAM PNMT, ALKBH3, ALKBH1 PRMT3 14/4885CARM1 59/4885PRMT6 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.