SCHEMBL9101017

SCHEMBL9101017

CCCNc1nc2c(c(N3C4CCC3CC(O)C4)n1)CCN2C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
GAA P10253 2/20 0.34
HPGD P15428 2/20 0.34
FLT3 P36888 2/20 0.32
TYRO3 Q06418 2/20 0.32
MERTK Q12866 2/20 0.32
GAS6 Q14393 2/20 0.32
GLA P06280 1/20 0.31
HSD17B10 Q99714 1/20 0.31
RCE1 Q9Y256 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
CYP2C9 P11712 1/20 0.30
MAPT P10636 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9104821 0.99 MEN1 (0.34) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL9108283 0.82 MEN1 (0.40) LMNAMEN1KMT2AKDM4EALDH1A1
Hydrochloric Acid SCHEMBL9106602 0.81 MEN1 (0.39) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL18073749 0.80 MEN1 (0.33) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL9912503 0.74 KMT2A (0.43) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL9104257 0.74 MERTK (0.36) FLT3TYRO3MERTK
SCHEMBL9105291 0.72 KMT2A (0.41) LMNAMEN1KMT2AKDM4EALDH1A1
Hydrochloric Acid SCHEMBL9105736 0.71 KMT2A (0.40) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL9107690 0.71 LMNA (0.43) LMNAMEN1KMT2AKDM4EALDH1A1
Hydrochloric Acid SCHEMBL9102432 0.70 LMNA (0.42) LMNAMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150374706-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. 2015-12-31 US claimed
EP-2855438-A2 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES Galleon Pharmaceuticals, Inc. (US) 2015-04-08 EP claimed
US-20140371224-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. 2014-12-18 US claimed
WO-2013181217-A2 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. (US) 2013-12-05 WO claimed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US claimed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US claimed
US-20240238303-A1 LARGE-CONDUCTANCE POTASSIUM CHANNEL MODULATORS, COMPOSITIONS THEREOF, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF ENALARE THERAPEUTICS INC (US) 2024-07-18 US disclosed
EP-4333852-A1 LARGE-CONDUCTANCE POTASSIUM CHANNEL MODULATORS, COMPOSITIONS THEREOF, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF Enalare Therapeutics Inc. (US) 2024-03-13 EP disclosed
WO-2023250141-A2 METHODS OF TREATING NEUROLOGICAL VENTILATORY INSUFFICIENCY ENALARE THERAPEUTICS INC. (US) 2023-12-28 WO disclosed
US-20230414624-A1 METHODS OF TREATING NEUROLOGICAL VENTILATORY INSUFFICIENCY ENALARE THERAPEUTICS INC (US) 2023-12-28 US disclosed
WO-2023225177-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT RESPIRATORY DEPRESSION IN PATIENTS ENALARE THERAPEUTICS INC. (US) 2023-11-23 WO disclosed
US-20230310440-A1 RESPIRATORY STIMULANT NASAL FORMULATIONS ENALARE THERAPEUTICS INC. 2023-10-05 US disclosed
WO-2023192602-A2 RESPIRATORY STIMULANT NASAL FORMULATIONS ENALARE THERAPEUTICS INC. (US) 2023-10-05 WO disclosed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US disclosed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US disclosed
WO-2012074999-A1 NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. (US) 2012-06-07 WO disclosed
WO-2012074999-A1 NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. (US) 2012-06-07 WO disclosed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US disclosed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US disclosed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases MTNR1B, CHRM3, ADRA2C LMNA 2124/4885MEN1 2860/4885KMT2A 1945/4885
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases PER2, SMPD4, NDUFB5 LMNA 719/4885MEN1 2898/4885KMT2A 3102/4885
US-20140371224-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES PER2, MTNR1B, NDUFB5 LMNA 843/4885MEN1 3195/4885KMT2A 2815/4885
US-20230310440-A1 RESPIRATORY STIMULANT NASAL FORMULATIONS ADRA2C, MTNR1B, MTNR1A LMNA 3538/4885MEN1 4161/4885KMT2A 2558/4885
US-20240238303-A1 LARGE-CONDUCTANCE POTASSIUM CHANNEL MODULATORS, COMPOSITIONS THEREOF, METHODS OF MANUFACTURING THEREOF, AND METHODS OF USE THEREOF KCNN2, KCNN1, KCNN3 LMNA 574/4885MEN1 3506/4885KMT2A 1267/4885
US-20150374706-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES PER2, SMPD4, NDUFB5 LMNA 719/4885MEN1 2898/4885KMT2A 3102/4885
US-20230414624-A1 METHODS OF TREATING NEUROLOGICAL VENTILATORY INSUFFICIENCY SDHA, NDUFB7, OTC LMNA 1597/4885MEN1 2667/4885KMT2A 2683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.