Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472086 | 0.84 | EPHX1 (0.54) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL11599241 | 0.81 | PTGS1 (0.56) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL9445447 | 0.81 | CXCR1 (0.49) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL27959311 | 0.80 | PTGS1 (0.60) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL13491995 | 0.80 | PTGS1 (0.50) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL452233 | 0.80 | PTGS1 (0.60) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL1531205 | 0.79 | PTGS1 (0.53) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL10711912 | 0.79 | ALDH1A1 (0.63) | CYP2C9AKR1C3SMN1; SMN2ALDH1A1 | |
| SCHEMBL28841028 | 0.78 | ALDH1A1 (0.43) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL21064585 | 0.78 | PTGS1 (0.57) | PTGS1PTGS2LMNACYP2C9AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116732536-A | Method for synthesizing ibuprofen intermediate | 上海颐碳化学科技有限公司 | 2023-09-12 | — | — | CN | claimed |
| EP-2272853-B1 | SPIRO PHOSPHORUS-OXAZOLINE, SYNTHESIS AND USE THEREOF | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2014-08-27 | — | — | EP | claimed |
| US-8450493-B2 | Spiro phosphine-oxazoline, preparation method and application thereof | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2013-05-28 | — | — | US | claimed |
| US-20110118472-A1 | Spiro Phosphine-Oxazoline, Preparation Method and Application thereof | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-05-19 | — | — | US | claimed |
| EP-2272853-A1 | SPIRO PHOSPHORUS-OXAZOLINE, SYNTHESIS AND USE THEREOF | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-01-12 | — | — | EP | claimed |
| US-5223640-A | Regioselectively silylcarbonylating arylacetylene, oxidizing, desilylating, hydrogenating | HOECHST CELANESE CORPORATION (US) | 1993-06-29 | — | — | US | claimed |
| US-5202472-A | Hydrogenation of an optically active 2-phenylacrylic acid derivative using a nickel acetylacetonate and a chiral phosphine | ETHYL CORPORATION (US) | 1993-04-13 | — | — | US | claimed |
| US-5198576-A | Stereospecific hydrogenation of unsaturated acids | ETHYL CORPORATION (US) | 1993-03-30 | — | — | US | claimed |
| US-5190905-A | Phosphine ligand | ETHYL CORPORATION (US) | 1993-03-02 | — | — | US | claimed |
| US-5187136-A | Asymmetric hydrogenation of aromatic-substituted olefins using organorhenium catalyst | ETHYL CORPORATION (US) | 1993-02-16 | — | — | US | claimed |
| US-5187281-A | Using a chiral phosphine compound | ETHYL CORPORATION (US) | 1993-02-16 | — | — | US | claimed |
| US-5187135-A | And chiral phosphine compound | ETHYL CORPORATION (US) | 1993-02-16 | — | — | US | claimed |
| US-5177231-A | Asymmetric hydrogenation of aromatic-substituted olefins using cationic ruthenium(III) complexes | ETHYL CORPORATION (US) | 1993-01-05 | — | — | US | claimed |
| US-4762948-A | USING METALLOCENYL PHOSPHINE REDUCING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-09 | — | — | US | claimed |
| JP-53050138-A | — | — | None | — | — | JP | disclosed |
| JP-61112087-A | — | — | None | — | — | JP | disclosed |
| CN-116732536-A | Method for synthesizing ibuprofen intermediate | 上海颐碳化学科技有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-4188491-A | PREPARING 2-(4-BIPHENYLYL)PROPIONIC ACIDS BY REACTING BIPHENYLYLMAGNESIUM BROMIDES WITH SODIUM PYRUVATE, ACIDIFYING | THE BOOTS COMPANY LIMITED (GB) | 1980-02-12 | — | — | US | disclosed |
| JP-S5350138-A | NOVEL ACRYLIC ACID ESTER DERIVATIVES | HISAMITSU PHARMACEUT CO INC | 1978-05-08 | — | — | JP | disclosed |
| JP-S05350138-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118472-A1 | Spiro Phosphine-Oxazoline, Preparation Method and Application thereof | ADH1A, ADH1C, ALDH7A1 | PTGS1 1777/4885PTGS2 2712/4885LMNA 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.