SCHEMBL9913178

SCHEMBL9913178

CC(=O)OCC(O)COCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(CCCOCC(O)CO)O[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.37
KDM4E B2RXH2 1/20 0.32
DUSP3 P51452 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.32
PLA2G2C Q5R387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13006675 0.98 USP2 (0.38) USP2KDM4EDUSP3MEN1KMT2A
SCHEMBL9913180 0.91 USP2 (0.41) USP2KDM4EDUSP3MEN1KMT2A
SCHEMBL13006674 0.89 USP2 (0.38) USP2PLA2G2C
SCHEMBL35419 0.89 USP2 (0.34) USP2KDM4EMEN1KMT2A
SCHEMBL13006671 0.88 USP2 (0.43) USP2KDM4EDUSP3MEN1KMT2A
SCHEMBL20437548 0.88 USP2 (0.46) USP2
SCHEMBL11925337 0.88 USP2 (0.46) USP2
SCHEMBL20437550 0.86 USP2 (0.47) USP2PLA2G2C
SCHEMBL27273268 0.85 USP2 (0.44) USP2
SCHEMBL27273267 0.85 USP2 (0.44) USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198473-B2 Process for preparing organically modified siloxanes EVONIK GOLDSCHMIDT GMBH (DE) 2012-06-12 US disclosed
US-20100056818-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES EVONIK GOLDSCHMIDT GMBH (DE) 2010-03-04 US disclosed
US-7635581-B2 Process for preparing organically modified siloxanes GOLDSCHMIDT GMBH (DE) 2009-12-22 US disclosed
US-20070184006-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES GOLDSCHMIDT GMBH (DE) 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070184006-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES HSD17B12, CYP51A1, ESD USP2 497/4885KDM4E 563/4885DUSP3 4483/4885
US-20100056818-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES HSD17B12, CYP51A1, ESD USP2 497/4885KDM4E 563/4885DUSP3 4483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.