SCHEMBL35419

SCHEMBL35419

CC(=O)OCC(O)COCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP2 O75604 4/20 0.34
ALDH1A1 P00352 4/20 0.34
CYP3A4 P08684 3/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
LPAR5 Q9H1C0 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
HTT P42858 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13006675 0.91 USP2 (0.38) USP2MEN1KMT2AKDM4E
SCHEMBL9913178 0.89 USP2 (0.37) USP2MEN1KMT2AKDM4E
SCHEMBL11954167 0.89 LPAR5 (0.32) USP2CYP3A4LPAR5CYP1A2CYP2C19
SCHEMBL16852332 0.86 TSHR (0.41) ALDH1A1LPAR5
SCHEMBL331864 0.86 TSHR (0.41) ALDH1A1LPAR5
SCHEMBL18176161 0.85 TSHR (0.40) ALDH1A1LPAR5
SCHEMBL12889087 0.85 USP2 (0.35) USP2ALDH1A1CYP3A4MAPTHPGD
SCHEMBL410909 0.83 TSHR (0.41) ALDH1A1CYP3A4HPGDTP53LPAR5
SCHEMBL13967786 0.83 USP2 (0.30) USP2
SCHEMBL27273321 0.82 USP2 (0.42) USP2CYP3A4LPAR5CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638613-B2 Ophthalmic lenses and their manufacture by in-mold modification JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-05-26 US disclosed
EP-4408852-B1 ANTHRAQUINONE-FUNCTIONALIZED POLYMERIZATION INITIATORS AND THEIR USE IN THE MANUFACTURE OF OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE (US) 2026-04-08 EP disclosed
US-12595370-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-04-07 US disclosed
US-12595371-B2 Contact lens with improved vision break-up time JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-04-07 US disclosed
US-20260070882-A1 PHOTOSTABLE MIMICS OF MACULAR PIGMENT JOHNSON & JOHNSON VISION CARE (US) 2026-03-12 US disclosed
EP-4707342-A2 CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES Johnson & Johnson Vision Care, Inc. (US) 2026-03-11 EP disclosed
US-20260062386-A1 POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT JOHNSON & JOHNSON VISION CARE (US) 2026-03-05 US disclosed
EP-4408899-B9 AMIDE-FUNCTIONALIZED POLYMERIZATION INITIATORS AND THEIR USE IN THE MANUFACTURE OF OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE (US) 2026-02-18 EP disclosed
EP-4165465-B1 SYSTEMS AND METHODS FOR INDICATING THE TIME ELAPSED SINCE THE OCCURRENCE OF A TRIGGERING EVENT JOHNSON & JOHNSON VISION CARE (US) 2026-02-18 EP disclosed
US-20260043940-A1 N-VINYL OXAZOLIDINONE MONOMERS, POLYMERS THEREFROM, AND USE IN OPHTHALMIC DEVICES JOHNSON & JOHNSON VISION CARE (US) 2026-02-12 US disclosed
EP-2566911-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME Johnson & Johnson Vision Care, Inc. (US) 2013-03-13 EP disclosed
US-8222353-B2 Wettable hydrogels comprising acyclic polyamides JOHNSON & JOHNSON VISION CARE, INC. (US) 2012-07-17 US disclosed
US-20110294914-A1 WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES JOHNSON & JOHNSON VISION CARE, INC. 2011-12-01 US disclosed
WO-2011140318-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2011-11-10 WO disclosed
US-20110275734-A1 NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. 2011-11-10 US disclosed
US-8022158-B2 Wettable hydrogels comprising acyclic polyamides JOHNSON & JOHNSON VISION CARE, INC. (US) 2011-09-20 US disclosed
US-7786185-B2 Wettable hydrogels comprising acyclic polyamides JOHNSON & JOHNSON VISION CARE, INC. (US) 2010-08-31 US disclosed
US-20100151123-A1 WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES JOHNSON & JOHNSON VISION CARE, INC. 2010-06-17 US disclosed
EP-1720943-B1 WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES JOHNSON & JOHNSON VISION CARE (US) 2009-02-11 EP disclosed
US-20080045612-A1 Wettable hydrogels comprising acyclic polyamides JOHNSON & JOHNSON VISION CARE, INC 2008-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100151123-A1 WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES CRYAA, UACA, CRYZ USP2 360/4885ALDH1A1 4436/4885CYP3A4 4533/4885
US-12595370-B2 Polymerizable absorbers of UV and high energy visible light NLRP3, NLRP1, XDH USP2 819/4885ALDH1A1 738/4885CYP3A4 19/4885
US-20260062386-A1 POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT ERCC1, MCM6, GPR6 USP2 3865/4885ALDH1A1 3065/4885CYP3A4 318/4885
US-12595371-B2 Contact lens with improved vision break-up time CUTA, VEGFA, CASP14 USP2 1719/4885ALDH1A1 3458/4885CYP3A4 325/4885
US-12638613-B2 Ophthalmic lenses and their manufacture by in-mold modification UACA, AXL, CRYZ USP2 1733/4885ALDH1A1 1768/4885CYP3A4 1323/4885
US-20260070882-A1 PHOTOSTABLE MIMICS OF MACULAR PIGMENT CRY1, CRY2, XPA USP2 4165/4885ALDH1A1 3685/4885CYP3A4 1582/4885
US-20260043940-A1 N-VINYL OXAZOLIDINONE MONOMERS, POLYMERS THEREFROM, AND USE IN OPHTHALMIC DEVICES CARM1, HVCN1, OGFOD1 USP2 955/4885ALDH1A1 455/4885CYP3A4 1625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.