Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13880875 | 0.85 | PRKCA (0.36) | PRKCAALDH1A1TLR4 | |
| SCHEMBL14003359 | 0.85 | PRKCA (0.36) | PRKCAALDH1A1TLR4 | |
| SCHEMBL9913500 | 0.83 | — | — | |
| SCHEMBL767850 | 0.83 | — | — | |
| SCHEMBL9908704 | 0.83 | — | — | |
| SCHEMBL9908702 | 0.78 | — | — | |
| SCHEMBL18750466 | 0.78 | — | — | |
| SCHEMBL14559545 | 0.77 | PRKCA (0.31) | PRKCA | |
| SCHEMBL13707236 | 0.77 | PRKCA (0.31) | PRKCA | |
| SCHEMBL767953 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120219571-A1 | COMBINATION MOTIF IMMUNE STIMULATORY OLIGONUCLEOTIDES WITH IMPROVED ACTIVITY | COLEY PHARMACEUTICAL GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-8198251-B2 | Combination motif immune stimulatory oligonucleotides with improved activity | COLEY PHARMACEUTICAL GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219571-A1 | COMBINATION MOTIF IMMUNE STIMULATORY OLIGONUCLEOTIDES WITH IMPROVED ACTIVITY | STING1, IFNG, RNGTT | PRKCA 390/4885ALDH1A1 4766/4885TLR4 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.