Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MMP12 | P39900 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890509 | 0.91 | LMNA (0.58) | LMNAL3MBTL1MMP12FFAR1FFAR4 | |
| SCHEMBL8888799 | 0.90 | LMNA (0.57) | LMNAL3MBTL1MMP12FFAR1FFAR4 | |
| SCHEMBL8890500 | 0.90 | LMNA (0.57) | LMNAL3MBTL1MMP12FFAR1FFAR4 | |
| SCHEMBL8889406 | 0.90 | LMNA (0.57) | LMNAL3MBTL1MMP12FFAR1FFAR4 | |
| SCHEMBL614649 | 0.87 | SMN1; SMN2 (0.56) | LMNAL3MBTL1ALDH1A1PPARGPPARA | |
| SCHEMBL991355 | 0.87 | SMN1; SMN2 (0.56) | LMNAL3MBTL1ALDH1A1PPARGPPARA | |
| SCHEMBL820513 | 0.87 | SMN1; SMN2 (0.56) | LMNAL3MBTL1ALDH1A1PPARGPPARA | |
| SCHEMBL4756342 | 0.86 | L3MBTL1 (0.65) | LMNAL3MBTL1FFAR1FFAR4NR1H4 | |
| SCHEMBL5375675 | 0.86 | L3MBTL1 (0.65) | LMNAL3MBTL1FFAR1FFAR4NR1H4 | |
| SCHEMBL1596779 | 0.86 | L3MBTL1 (0.65) | LMNAL3MBTL1FFAR1FFAR4NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |