SCHEMBL9914256

SCHEMBL9914256

COc1ccc(C(c2ccc(Oc3ccc(S(=O)(=O)c4ccc(C)cc4)cc3)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.58
HTT P42858 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PKM P14618 2/20 0.53
ALDH1A1 P00352 4/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GAA P10253 2/20 0.46
RAPGEF4 Q8WZA2 1/20 0.46
ACHE P22303 2/20 0.45
BCHE P06276 1/20 0.45
MAPT P10636 3/20 0.41
CYP1A2 P05177 1/20 0.41
MAPK1 P28482 1/20 0.41
MMP2 P08253 2/20 0.40
MMP9 P14780 2/20 0.40
MMP8 P22894 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12198430 1.00 HSD11B1 (0.58) HSD11B1HTTSMN1; SMN2PKMALDH1A1
SCHEMBL13910299 0.96 HSD11B1 (0.54) HSD11B1HTTSMN1; SMN2PKMALDH1A1
SCHEMBL13953063 0.96 HSD11B1 (0.54) HSD11B1HTTSMN1; SMN2PKMALDH1A1
SCHEMBL14365486 0.94 HTT (0.61) HSD11B1HTTSMN1; SMN2PKMALDH1A1
SCHEMBL822939 0.94 HTT (0.61) HSD11B1HTTSMN1; SMN2PKMALDH1A1
SCHEMBL16606653 0.89 HTT (0.58) HSD11B1HTTSMN1; SMN2PKMALDH1A1
SCHEMBL13120644 0.89 HTT (0.53) HSD11B1HTTSMN1; SMN2PKMALDH1A1
SCHEMBL12277221 0.88 ACHE (0.54) HSD11B1ALDH1A1TDP1L3MBTL1ACHE
SCHEMBL12260130 0.88 ACHE (0.54) HSD11B1ALDH1A1TDP1L3MBTL1ACHE
SCHEMBL12451153 0.88 PKM (0.65) HSD11B1HTTSMN1; SMN2PKMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10569232-B2 Copolymers for making membranes BASF SE (DE) 2020-02-25 US disclosed
EP-2129716-B1 THERMOPLASTIC COMPOSITIONS CONTAINING MICROSPHERES SOLVAY SPECIALTY POLYMERS USA (US) 2018-05-23 EP disclosed
US-20180081273-A1 RESIN COMPOSITION, METHOD FOR FORMING PATTERN USING THE SAME, AND METHOD FOR SYNTHESIZING POLYMER NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-22 US disclosed
US-20180056245-A1 PROCESSES FOR REDUCING THE FOULING OF SURFACES BASF SE (DE) 2018-03-01 US disclosed
US-20170333849-A1 COPOLYMERS FOR MAKING MEMBRANES BASF SE (DE) 2017-11-23 US disclosed
US-20170333849-A1 COPOLYMERS FOR MAKING MEMBRANES BASF SE (DE) 2017-11-23 US disclosed
US-9764276-B2 Resin composition and carbon dioxide gas separation membrane SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-19 US disclosed
US-9764276-B2 Resin composition and carbon dioxide gas separation membrane SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-19 US disclosed
US-20170253764-A1 FILM-FORMING COMPOSITION INCLUDING THERMOSETTING RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-09-07 US disclosed
EP-2176318-B1 FLAME RESISTANT SULFONE POLYMERS SOLVAY SPECIALTY POLYMERS USA (US) 2017-05-24 EP disclosed
US-20090197763-A1 Aromatic block copolymer, decomposition method thereof and analysis method using the decomposition method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-06 US disclosed
US-20090117438-A1 POLYMER ELECTROLYTE, AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL THAT ARE USING THE POLYMER ELECTROLYTE SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2009-05-07 US disclosed
WO-2009019239-A1 FLAME RESISTANT SULFONE POLYMERS SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2009-02-12 WO disclosed
WO-2008090235-A2 THERMOPLASTIC COMPOSITIONS CONTAINING MICROSPHERES SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2008-07-31 WO disclosed
US-20080142443-A1 POLYARYLETHER MEMBRANES GENERAL ELECTRIC (US) 2008-06-19 US disclosed
US-20080142442-A1 hollow fiber modules comprising blends of polyphenylene ethers block polymers and polyvinylpyrrolidone, used for blood dialysis and filtration GENERAL ELECTRIC (US) 2008-06-19 US disclosed
US-20070281195-A1 Block copolymer and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2007-12-06 US disclosed
US-20070231671-A1 Catalyst Material For Use In Fuel Cell, Catalyst Membrane, Membrane Electrode Assembly and Fuel Cell FUJIFILM CORPORATION 2007-10-04 US disclosed
US-20070166591-A1 POLYMER ELECTROLYTE COMPOSITION AND APPLICATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-07-19 US disclosed
US-20070066759-A1 Block copolymers and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-22 US disclosed