Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14678192 | 0.87 | AGPAT2 (0.36) | GRM2HTR2BHTR6PIK3CAAGPAT2 | |
| SCHEMBL22190184 | 0.86 | CARM1 (0.33) | CARM1 | |
| SCHEMBL15868318 | 0.83 | TYK2 (0.36) | GRM2DRD2DRD4HTR2BHTR6 | |
| SCHEMBL22036970 | 0.83 | POLB (0.38) | GRM2DRD2DRD4 | |
| SCHEMBL29431625 | 0.82 | HTR2B (0.38) | GRM2HTR2BHTR6PIK3CACARM1 | |
| SCHEMBL14684635 | 0.82 | HTR2B (0.38) | GRM2HTR2BHTR6PIK3CACARM1 | |
| SCHEMBL14677498 | 0.82 | AGPAT2 (0.33) | GRM2DRD2DRD4HTR2BHTR6 | |
| SCHEMBL9914987 | 0.82 | AGPAT2 (0.35) | GRM2HTR2BHTR6PIK3CAAGPAT2 | |
| SCHEMBL17986769 | 0.81 | DRD2 (0.39) | GRM2DRD2DRD4HTR2BHTR6 | |
| SCHEMBL17986770 | 0.81 | GRM2 (0.39) | GRM2DRD2DRD4HTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207460-B | Fused heterocyclic compound having cycloalkylpyridyl group or salt thereof, agricultural and horticultural insecticide containing the same, and method for using the same | 日本农药株式会社 | 2020-09-15 | — | — | CN | disclosed |
| EP-3252046-B1 | FUSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AND AGRICULTURAL OR HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND AND USE METHOD THEREFOR | NIHON NOHYAKU CO LTD (JP) | 2020-04-01 | — | — | EP | disclosed |
| US-10266552-B2 | Condensed heterocyclic compound having cycloalkylpyridyl group or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2019-04-23 | — | — | US | disclosed |
| US-20180002347-A1 | CONDENSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2018-01-04 | — | — | US | disclosed |
| EP-3252046-A1 | FUSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AND AGRICULTURAL OR HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND AND USE METHOD THEREFOR | Nihon Nohyaku Co., Ltd. (JP) | 2017-12-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180002347-A1 | CONDENSED HETEROCYCLIC COMPOUND HAVING CYCLOALKYLPYRIDYL GROUP OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | DDT, HCN3, HCN1 | GRM2 274/4885DRD2 529/4885DRD4 504/4885 |
| US-10266552-B2 | Condensed heterocyclic compound having cycloalkylpyridyl group or salt thereof, agricultural and horticultural insecticide comprising the compound, and method for using the insecticide | DDT, HCN3, HCN1 | GRM2 274/4885DRD2 529/4885DRD4 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.