Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11570198 | 0.87 | HDAC3 (0.50) | NPC1RAB9ACES2CES1KCNK9 | |
| SCHEMBL9915152 | 0.85 | RAB9A (0.66) | NPC1RAB9ACES2CES1KCNK9 | |
| SCHEMBL9274738 | 0.85 | ALOX15 (0.52) | NPC1RAB9ACES1KCNK9SMN1; SMN2 | |
| SCHEMBL9915156 | 0.82 | POLB (0.57) | NPC1RAB9ACES2CES1SMN1; SMN2 | |
| SCHEMBL9915082 | 0.80 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL28690251 | 0.80 | NPC1 (0.71) | NPC1RAB9ACES2CES1KCNK9 | |
| SCHEMBL4927732 | 0.80 | GAA (0.75) | NPC1RAB9ACES2CES1KCNK9 | |
| SCHEMBL19002182 | 0.79 | KCNK9 (0.55) | NPC1RAB9AKCNK9SMN1; SMN2ALDH1A1 | |
| SCHEMBL15281686 | 0.79 | NPC1 (0.54) | NPC1RAB9AKCNK9SMN1; SMN2ALDH1A1 | |
| SCHEMBL9915113 | 0.79 | NPC1 (0.54) | NPC1RAB9AKCNK9SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096504-B2 | Controlled chemical release of hydrogen sulfide | WASHINGTON STATE UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130253051-A1 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | WASHINGTON STATE UNIVERSITY (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2012075242-A2 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253051-A1 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | GSR, AR, GRHPR | NPC1 2731/4885RAB9A 3033/4885CES2 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.