Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15279027 | 0.81 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19GLASMN1; SMN2 | |
| SCHEMBL10976072 | 0.77 | CYP1A2 (0.36) | CYP1A2CYP2C9CYP2C19GLASMN1; SMN2 | |
| SCHEMBL9915307 | 0.72 | RAB9A (0.43) | SMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9915431 | 0.72 | NOTUM (0.36) | CYP1A2CYP2C9CYP2C19CA12CA1 | |
| SCHEMBL13412631 | 0.70 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19GLASMN1; SMN2 | |
| SCHEMBL30485172 | 0.66 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19GLASMN1; SMN2 | |
| SCHEMBL30485171 | 0.66 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19GLASMN1; SMN2 | |
| SCHEMBL7755326 | 0.66 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19GLASMN1; SMN2 | |
| SCHEMBL2605642 | 0.66 | CSNK2A1 (0.60) | CYP1A2CYP2C9CYP2C19GLASMN1; SMN2 | |
| SCHEMBL7044142 | 0.65 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19TSHRTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120302542-A1 | MONOBACTAMS | PFIZER INC | 2012-11-29 | — | — | US | disclosed |
| WO-2012073138-A1 | MONOBACTAMS | PFIZER INC. (US) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302542-A1 | MONOBACTAMS | MGAM, MGAM2, BPGM | CYP1A2 957/4885CYP2C9 975/4885CYP2C19 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.