Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29462117 | 0.93 | MAPT (0.55) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL261845 | 0.93 | MAPT (0.55) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL30887233 | 0.92 | NPC1 (0.56) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL13178023 | 0.88 | MAPT (0.64) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL20274482 | 0.88 | NPC1 (0.50) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL4253388 | 0.86 | MAPT (0.47) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL8032993 | 0.85 | MAPT (0.47) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL20262009 | 0.85 | NPC1 (0.45) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL14838826 | 0.85 | MEN1 (0.47) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL26937995 | 0.84 | MAPT (0.44) | NPC1RAB9AMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377464-B2 | Polymerizable surfactants and their use as device forming comonomers | BAUSCH & LOMB INCORPORATED (US) | 2013-02-19 | — | — | US | disclosed |
| US-8377464-B2 | Polymerizable surfactants and their use as device forming comonomers | BAUSCH & LOMB INCORPORATED (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120157565-A1 | Polymerizable Surfactants and Their Use as Device Forming Comonomers | BAUSCH HEALTH US, LLC | 2012-06-21 | — | — | US | disclosed |
| US-20120157565-A1 | Polymerizable Surfactants and Their Use as Device Forming Comonomers | BAUSCH HEALTH US, LLC | 2012-06-21 | — | — | US | disclosed |
| US-8197841-B2 | Polymerizable surfactants and their use as device forming comonomers | BAUSCH & LOMB INCORPORATED (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197841-B2 | Polymerizable surfactants and their use as device forming comonomers | BAUSCH & LOMB INCORPORATED (US) | 2012-06-12 | — | — | US | disclosed |
| EP-1828813-B1 | POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS | BAUSCH & LOMB (US) | 2010-02-10 | — | — | EP | disclosed |
| WO-2007149083-A1 | POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2007-12-27 | — | — | WO | disclosed |