SCHEMBL261845

SCHEMBL261845

C=C(C)C(=O)OCCc1ccc(Nc2ccc(Nc3ccc(CCOC(=O)C(=C)C)cc3)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.55
▸ MEN1 O00255 3/20 0.55
▸ KMT2A Q03164 3/20 0.55
▸ NPC1 O15118 2/20 0.55
▸ RAB9A P51151 2/20 0.55
▸ LMNA P02545 2/20 0.55
▸ MAPK1 P28482 2/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55
▸ TDP1 Q9NUW8 1/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ SIRT2 Q8IXJ6 2/20 0.43
▸ MTOR P42345 1/20 0.43
▸ CYP1A2 P05177 2/20 0.41
▸ TSHR P16473 1/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ PABPC1 P11940 1/20 0.40
▸ PRKCA P17252 1/20 0.40
▸ PHLPP2 Q6ZVD8 1/20 0.40
▸ P2RY2 P41231 2/20 0.39
▸ P2RY4 P51582 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29462117 1.00 MAPT (0.55) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL20274482 0.95 NPC1 (0.50) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL13178023 0.95 MAPT (0.64) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL9915558 0.93 NPC1 (0.48) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL4253388 0.92 MAPT (0.47) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL8032993 0.92 MAPT (0.47) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL14838826 0.91 MEN1 (0.47) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL26937995 0.91 MAPT (0.44) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL16011446 0.91 MAPT (0.45) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL14992726 0.90 MEN1 (0.46) MAPTMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 — — US claimed
EP-4519721-B1 RADIATION BLOCKERS FOR CONTACT LENSES COOPERVISION INT LTD (GB) 2025-10-01 — — EP claimed
WO-2023228055-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 — — WO claimed
US-20230374306-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 — — US claimed
US-11372267-B2 Contact lens product LARGAN MEDICAL CO., LTD. (TW) 2022-06-28 — — US claimed
US-20200150460-A1 CONTACT LENS PRODUCT LARGAN MEDICAL CO., LTD. (TW) 2020-05-14 — — US claimed
US-10578889-B2 Contact lens product LARGAN MEDICAL CO., LTD. (TW) 2020-03-03 — — US claimed
US-20190317339-A1 CONTACT LENS PRODUCT LARGAN MEDICAL CO., LTD. (TW) 2019-10-17 — — US claimed
US-10371966-B2 Contact lens product LARGAN MEDICAL CO., LTD. (TW) 2019-08-06 — — US claimed
EP-2785296-B1 OCULAR MASK HAVING SELECTIVE SPECTRAL TRANSMISSION ACUFOCUS INC (US) 2018-06-20 — — EP claimed
US-20170227790-A1 CONTACT LENS PRODUCT LARGAN MEDICAL CO., LTD. (TW) 2017-08-10 — — US claimed
WO-2008103754-A2 AESTHETIC INTRAOCULAR IMPLANT TSENG JANET C (US) 2008-08-28 — — WO claimed
EP-0396376-B1 Polymerizable dye BAUSCH & LOMB (US) 1994-12-28 — — EP claimed
US-5055602-A POLYMERIZABLE DYE BAUSCH & LOMB INCORPORATED (US) 1991-10-08 — — US claimed
US-4997897-A Unsaturated esters or amides of aminoanthraquinone dyes BAUSCH & LOMB INCORPORATED (US) 1991-03-05 — — US claimed
EP-0396376-A1 Polymerizable dye BAUSCH & LOMB INCORPORATED (US) 1990-11-07 — — EP claimed
JP-3072576-A — — None — — JP disclosed
US-20260147141-A1 SURFACE MODIFIED SILICONE OPHTHALMIC DEVICES BAUSCH + LOMB IRELAND LIMITED (IE) 2026-05-28 — — US disclosed
WO-1994003324-A1 PROCESS FOR MAKING SILICONE CONTAINING HYDROGEL LENSES BAUSCH & LOMB INCORPORATED (US) 1994-02-17 — — WO disclosed
JP-H0372576-A POLYMERIZABLE DYE BAUSCH & LOMB INC 1991-03-27 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L MAPT 453/4885MEN1 2259/4885KMT2A 3487/4885
US-20260147141-A1 SURFACE MODIFIED SILICONE OPHTHALMIC DEVICES EPCAM, STIM1, SMCHD1 MAPT 3639/4885MEN1 3210/4885KMT2A 2962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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