SCHEMBL4253388

SCHEMBL4253388

C=C(C)C(=O)OCCc1ccc(Nc2cccc3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.47
▸ MEN1 O00255 6/20 0.47
▸ KMT2A Q03164 6/20 0.47
▸ RAB9A P51151 4/20 0.47
▸ MAPK1 P28482 3/20 0.47
▸ NPC1 O15118 3/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ L3MBTL1 Q9Y468 2/20 0.47
▸ LMNA P02545 2/20 0.47
▸ NPSR1 Q6W5P4 2/20 0.47
▸ MAOA P21397 1/20 0.46
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ PABPC1 P11940 2/20 0.41
▸ EGFR P00533 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.38
▸ POLB P06746 2/20 0.38
▸ GAA P10253 1/20 0.38
▸ DNMT1 P26358 1/20 0.38
▸ RAD52 P43351 1/20 0.38
▸ SMARCA2 P51531 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26937995 0.97 MAPT (0.44) MAPTMEN1KMT2ARAB9AMAPK1
SCHEMBL261845 0.92 MAPT (0.55) MAPTMEN1KMT2ARAB9AMAPK1
SCHEMBL29462117 0.92 MAPT (0.55) MAPTMEN1KMT2ARAB9AMAPK1
SCHEMBL16011446 0.90 MAPT (0.45) MAPTMEN1KMT2ARAB9AMAPK1
SCHEMBL23213406 0.88 MAOA (0.45) MAPTMEN1KMT2ARAB9AMAPK1
SCHEMBL13178023 0.88 MAPT (0.64) MAPTMEN1KMT2ARAB9AMAPK1
SCHEMBL20274482 0.88 NPC1 (0.50) MAPTMEN1KMT2ARAB9AMAPK1
SCHEMBL9915558 0.86 NPC1 (0.48) MAPTMEN1KMT2ARAB9AMAPK1
SCHEMBL8032993 0.85 MAPT (0.47) MAPTMEN1KMT2ARAB9AMAPK1
SCHEMBL13370294 0.85 MAPT (0.44) MAPTMEN1KMT2ARAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117264216-A Fluorine-containing macromolecular organic silicon monomer for silicon hydrogel contact lens and preparation method and application thereof 华诺森(武汉)生物医药技术有限公司 2023-12-22 — — CN disclosed
CN-116948139-A Hydrophilic macromolecular organic silicon monomer for cornea contact lens and preparation method and application thereof 华诺森(武汉)生物医药技术有限公司 2023-10-27 — — CN disclosed
CN-116589685-A Hydrophilic macromolecular organic silicon monomer for silicon hydrogel contact lens and preparation method and application thereof 华诺森(武汉)生物医药技术有限公司 2023-08-15 — — CN disclosed
CN-116535651-A Macromolecular organic silicon monomer for silicon hydrogel contact lens and preparation method and application thereof 华诺森(武汉)生物医药技术有限公司 2023-08-04 — — CN disclosed
CN-116194805-A9 Colored contact lens 库博光学国际有限公司 2023-07-21 — — CN disclosed
CN-116194805-A Colored contact lens 库博光学国际有限公司 2023-05-30 — — CN disclosed
CN-114096911-A Ophthalmic medical devices comprising photochromic polymers and methods of making the same 株式会社目立康 2022-02-25 — — CN disclosed
CN-112912788-A Medical device and method for manufacturing same 东丽株式会社 2021-06-04 — — CN disclosed
CN-112703213-A Polymer material 株式会社目立康 2021-04-23 — — CN disclosed
CN-110603061-A Medical instrument 东丽株式会社 2019-12-20 — — CN disclosed
CN-1301353-A Method of polymerizing contact lenses BAUSCH & LOMB INCORP (US) 2001-06-27 — — CN disclosed
CN-1299388-A Plasma surface treatment of silicone hydrogen contact lenses BAUSCH & LOBM INC (US) 2001-06-13 — — CN disclosed
EP-0683436-B1 Liquid toners utilizing highly fluorinated solvents MINNESOTA MINING & MFG (US) 2000-03-22 — — EP disclosed
US-5663024-A Liquid toners with hydrocarbon solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-02 — — US disclosed
US-5599886-A Liquid toners with hydrocarbon solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-02-04 — — US disclosed
US-5530053-A ELECTROSTATIC TONERS COMPRISING POLYMERIC DYES CONTAINING FLUORINATED MACROMERS COMPLEXED WITH A METAL CHARGE CONTROLLER; ANTIAGGLOMERANTS; QUICK-DRYING; TRANSFERABILITY; NON-FLAMMABLE; ELECTROGRAPHY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-25 — — US disclosed
US-5530067-A GRAFT FLUOROPOLYMERIC DYES FOR USE ELECTROGRAPHIC PROCESS; HIGH SPEED DRYING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-25 — — US disclosed
US-5521271-A Liquid toners with hydrocarbon solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-28 — — US disclosed
EP-0706095-A1 Liquid toners with hydrocarbon solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-10 — — EP disclosed
EP-0683436-A1 Liquid toners utilizing highly fluorinated solvents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-22 — — EP disclosed
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