SCHEMBL29462117

SCHEMBL29462117

C=C(C)C(=O)OCCc1ccc(Nc2ccc(Nc3ccc(CCOC(=O)C(=C)C)cc3)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.55
▸ MEN1 O00255 3/20 0.55
▸ KMT2A Q03164 3/20 0.55
▸ NPC1 O15118 2/20 0.55
▸ RAB9A P51151 2/20 0.55
▸ LMNA P02545 2/20 0.55
▸ MAPK1 P28482 2/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55
▸ TDP1 Q9NUW8 1/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ SIRT2 Q8IXJ6 2/20 0.43
▸ MTOR P42345 1/20 0.43
▸ CYP1A2 P05177 2/20 0.41
▸ TSHR P16473 1/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ PABPC1 P11940 1/20 0.40
▸ PRKCA P17252 1/20 0.40
▸ PHLPP2 Q6ZVD8 1/20 0.40
▸ P2RY2 P41231 2/20 0.39
▸ P2RY4 P51582 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261845 1.00 MAPT (0.55) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL20274482 0.95 NPC1 (0.50) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL13178023 0.95 MAPT (0.64) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL9915558 0.93 NPC1 (0.48) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL4253388 0.92 MAPT (0.47) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL8032993 0.92 MAPT (0.47) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL14838826 0.91 MEN1 (0.47) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL26937995 0.91 MAPT (0.44) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL16011446 0.91 MAPT (0.45) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL14992726 0.90 MEN1 (0.46) MAPTMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026105013-A1 CONTACT LENSES WITH COLOR FILTERING ZONE ALCON INC. (CH) 2026-05-21 — — WO claimed
US-20260133439-A1 CONTACT LENSES WITH COLOR FILTERING ZONE ALCON INC. (CH) 2026-05-14 — — US claimed
EP-4713721-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-03-25 — — EP claimed
EP-4713720-A2 HIGH-ENERGY-VIOLET-ABSORBING VINYLIC MONOMERS Alcon Inc. (CH) 2026-03-25 — — EP claimed
US-12577345-B2 Radiation blockers for contact lenses COOPERVISION INTERNATIONAL LIMITED (GB) 2026-03-17 — — US claimed
CN-119875000-A Method for reducing the residual monomer content in a polymer composition, composition capable of free radical polymerization, method for producing a polymer, polymer and use 沈阳康恩德医疗科技有限公司 2025-04-25 — — CN claimed
US-20250109234-A1 RADIATION BLOCKERS FOR CONTACT LENSES COOPERVISION INTERNATIONAL LIMITED (GB) 2025-04-03 — — US claimed
EP-4529621-A1 UV/HEVL-FILTERING CONTACT LENSES Alcon Inc. (CH) 2025-04-02 — — EP claimed
CN-119654577-A Radiation blocking agents for contact lenses 库博光学国际有限公司 2025-03-18 — — CN claimed
EP-4519721-A1 RADIATION BLOCKERS FOR CONTACT LENSES CooperVision International Limited (GB) 2025-03-12 — — EP claimed
WO-2025032504-A2 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2025-02-13 — — WO claimed
US-20250052927-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-02-13 — — US claimed
CN-119137510-A UV/HEVL filtering contact lenses 爱尔康公司 2024-12-13 — — CN claimed
US-20240392055-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-11-28 — — US claimed
WO-2024236526-A2 HIGH-ENERGY-VIOLET-ABSORBING VINYLIC MONOMERS ALCON INC. (CH) 2024-11-21 — — WO claimed
WO-2024236524-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-11-21 — — WO claimed
US-20240383865-A1 HIGH-ENERGY-VIOLET-ABSORBING VINYLIC MONOMERS ALCON INC (CH) 2024-11-21 — — US claimed
WO-2024236287-A1 RADIATION BLOCKERS FOR CONTACT LENSES COOPERVISION INTERNATIONAL LIMITED (GB) 2024-11-21 — — WO claimed
WO-2023228055-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 — — WO claimed
CN-114990904-A Energy-saving and environment-friendly dyeing process for Lyocell knitted fabric 青岛大学 2022-09-02 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260133439-A1 CONTACT LENSES WITH COLOR FILTERING ZONE MYO1G, STRA6, GJA1 MAPT 2948/4885MEN1 191/4885KMT2A 1852/4885
US-12577345-B2 Radiation blockers for contact lenses TBL3, TTLL12, TBL2 MAPT 170/4885MEN1 2040/4885KMT2A 1882/4885
US-20240383865-A1 HIGH-ENERGY-VIOLET-ABSORBING VINYLIC MONOMERS VCL, HBS1L, SAAL1 MAPT 189/4885MEN1 3178/4885KMT2A 1693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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