Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915611 | 0.81 | AKR1C3 (0.46) | DRD2USP2MAPTKMT2AALDH1A1 | |
| SCHEMBL12556830 | 0.81 | MAPT (0.58) | ALOX15MAPK1HSD17B10USP2SMN1; SMN2 | |
| SCHEMBL14617528 | 0.80 | ADRA2C (0.62) | DRD2ALOX15MAPK1SMN1; SMN2MAPT | |
| SCHEMBL9915612 | 0.78 | CHKA (0.57) | DRD2ALOX15USP2TSHRSMN1; SMN2 | |
| SCHEMBL164538 | 0.78 | LMNA (0.67) | CHRNA7SIGMAR1DRD2ALOX15CYP3A4 | |
| SCHEMBL576814 | 0.78 | LMNA (0.67) | CHRNA7SIGMAR1DRD2ALOX15CYP3A4 | |
| SCHEMBL16924853 | 0.78 | LMNA (0.67) | CHRNA7SIGMAR1DRD2ALOX15CYP3A4 | |
| SCHEMBL576454 | 0.78 | LMNA (0.67) | CHRNA7SIGMAR1DRD2ALOX15CYP3A4 | |
| SCHEMBL385012 | 0.78 | — | — | |
| SCHEMBL19962181 | 0.76 | ADRB1 (0.53) | TSHRSMN1; SMN2KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |